1. Genes and Variation 16-1 This section describes the main sources of heritable variation in a population. It also explains how phenotypes are expressed.

2. Introduction  Is the following sentence true or false? Mendel’s work on inheritance was published after Darwin’s lifetime. Mendel’s work on inheritance was published after Darwin’s lifetime.  FALSE

3. DARWIN’s ORIGIN of SPECIES  Which two important factors was Darwin unable to explain without an understanding of heredity?  He was unable to explain the source of variation and how heritable traits were passed from one generation to the next.

4. How Common Is Genetic Variation All organisms have additional __________that is “invisible” because it involves small differences in biochemical processes. All organisms have additional __________that is “invisible” because it involves small differences in biochemical processes. genetic variation

5. Variation and Gene Pools  A group of individuals of the same species that interbreed is a(an) ____.  population

6. GENE VARIATION  All of the genes in a population are called a(an)____.  gene pool

7. GENE VARIATION  Is the following sentence true or false?  A gene pool typically contains just one allele for each inheritable trait.  false

8. GENE VARIATION  The number of times that an allele occurs in a gene pool compared with the number of times other alleles for the same gene occur is called the _______ of the allele.  relative frequency

9. GENE VARIATION

10. Evolution of Populations Sources of Genetic Variation  What is a mutation?  It is any change in a sequence of DNA.

11. GENE VARIATION  Why do mutations occur?  They occur because of mistakes in the replication of DNA or as a result of radiation or chemicals in the environment.

12. GENE VARIATION GENE VARIATION  Circle the letter of each choice that is true about mutations.  They do not always change an amino acid

13. GENE VARIATION  Is the following sentence true or false?  Most heritable differences are due to gene shuffling that occurs during the production of gametes.   TRUE

14. GENE VARIATION  Circle the letter of each choice that is true about sexual reproduction.  It is a major source of variation in many populations.  It can produce many different phenotypes.  It can produce many different genetic combinations.

15. GENE VARIATION  Single-Gene and Polygenic Traits  Is the following sentence true or false?  The number of phenotypes produced for a given trait depends on how many genes control the trait.  TRUE

16. GENE VARIATION  Is the following sentence true or false?  Most traits are controlled by a single gene.  false

17. GENETIC VARIATION Polygenic Trait Single-Gene Trait Label the two graphs to show which one represents a single-gene trait and which one represents a polygenic trait.