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A PROSPECTIVE RANDOMIZED STUDY TO ASSESS THE EFFICACY OF POST- OPERATIVE NASAL MEDICATION AFTER ENDONASAL SURGERY Paul D.R.. Spragggs etal. The Journal.

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Presentation on theme: "A PROSPECTIVE RANDOMIZED STUDY TO ASSESS THE EFFICACY OF POST- OPERATIVE NASAL MEDICATION AFTER ENDONASAL SURGERY Paul D.R.. Spragggs etal. The Journal."— Presentation transcript:

1 A PROSPECTIVE RANDOMIZED STUDY TO ASSESS THE EFFICACY OF POST- OPERATIVE NASAL MEDICATION AFTER ENDONASAL SURGERY Paul D.R.. Spragggs etal. The Journal of Laryngology and Otology July 1995, Vol. 109, pp. 618-621. Treatment Groups.Alkaline nasal douche (n = 19).Betnosol drops (n = 17).0.5% Eplidrine drops (n = 20).Control (n= 19)

2 Outcome Nasal stuffiness as measured on a visual analogue scale

3 Analysis Mann whitney U. Test Glass rank biserial correlation Significant ( P<0.05) differences were found at all time intervals

4 Conclusion The use of these treatments should be encouraged to both improve the sensation of nasal patency and also aid clearance of debris from the nasal fossae.

5 Mean Visual Analogue Scores (VAS) and Standard Deviations (SD) for each group.

6 EFFICIENCY OF VIT. A. IN REDUCING PRE-SCHOOL CHILD MORTALITY 6 – 11 MONTHS Vit. AControl RR Malnourished 4.6% 6.6%1.4 Well nourished 1.3% 1.8%1.4 (3.5) (3.7) 12 – 72 MONTHS Malnourished 6% 8%1.3 Well nourished 0.4% 0.7% 1.75 (15) (11.4)

7 Effect of passive smoking on Ischaemic heart disease mortality of non smokers. A prospective study Garland et. al American Journal of Epidemiology Vol. 121. No. 5, 1985.

8 Subjects: Married women who never smoked aged 50 – 79. Exposure variable:Husbands’ smoking habit a)Never - 203b)Former - 395c)Current - 97 Follow up: 10 years Analysis: Adjustments done using Cox’s proportional Hazards model. Finding: Wives of current / past smoker had 14.9 time greater risk of CHD deaths Recommendation: Ban smoking in closed places.

9 Age adjusted 10 year mortality rate according to husband’s smoking status NeverFormerCurrent (n = 203)( n = 395) (n = 97) CHD Death rates 1.2% 3.6% 2.7% All causes 11% 11% 13.3%


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