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Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates Bradley Croy Doak, Bj ӧ rn Over, Fabrizio Giordanetto, Jan Kihlberg.

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Presentation on theme: "Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates Bradley Croy Doak, Bj ӧ rn Over, Fabrizio Giordanetto, Jan Kihlberg."— Presentation transcript:

1 Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates Bradley Croy Doak, Bj ӧ rn Over, Fabrizio Giordanetto, Jan Kihlberg Chemistry & Biology Volume 21, Issue 9, Pages 1115-1142 (September 2014) DOI: 10.1016/j.chembiol.2014.08.013 Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

5 Figure 4 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

6 Figure 5 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

7 Figure 6 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

8 Figure 7 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

9 Figure 8 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

10 Figure 9 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

11 Chemistry & Biology 2014 21, 1115-1142DOI: (10.1016/j.chembiol.2014.08.013) Copyright © 2014 Elsevier Ltd Terms and Conditions Terms and Conditions

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