1. The Clinical Application of Biocompatible Bone Grafts Steiner Biotechnology

2. What is bone? A collagen matrix containing many other proteins that becomes mineralized. The osteoblast does not produce mineralized bone but produces collagen that becomes mineralized after it is formed outside of the cell.

3. What is a biocompatible bone graft? Does not produce an inflammatory reaction. Produces normal bone. Fully resorbed. If a bone graft is not fully resorbed and does not produce normal bone the FDA does not allow implant placement in a site grafted with the graft material.

4. Why is biocompatibility Important If a bone graft produces inflammation sclerotic bone will be formed which does not have the ability to remodel. If bone cannot remodel and respond to changing forces the bone can fail and then the implant fails.

5. Examples of nonbiocompatible bone grafts. Allografts -mineralized human proteins BioOss – mineralized bovine proteins BioPlant Non resorbable ceramics Infuse an allograft in a xenograft Foundation Resorbable membranes made from foreign proteins

6. Examples of biocompatible bone grafts Synthograft 1 st generation BTCP Cerasorb 2 nd generation BTCP Osseoconduct 3 rd generation BTCP Calcium Sulfate Socket Graft Putty Sinus Graft Ridge Graft

7. Clinical Application of Biocompatible Bone Grafts Treating extraction sites of incisors or bicuspids in the esthetic zone that retain their socket walls and present with adequate bone between the socket walls and adjacent teeth.

8. Clinical Application of Biocompatible Bone Grafts Treating extraction sites of incisors or bicuspids that retain their socket walls but lack bone between the extraction socket and adjacent teeth.

9. Clinical Application of Biocompatible Bone Grafts Treating extraction sites that retain socket walls but suffer extensive bone loss making stability for immediate implant placement unpredictable.

10. Clinical Application of Biocompatible Bone Grafts Treating molar extraction sites that retain their socket walls.

11. Clinical Application of Biocompatible Bone Grafts Treating extraction sites that retain their socket walls but have a minor sinus perforation.

12. Clinical Application of Biocompatible Bone Grafts Treating extraction sites that retain their socket walls but have a significant sinus perforation.

13. Clinical Application of Biocompatible Bone Grafts Treating extraction sites for incisors or bicuspids that have a buccal dehiscence (loss of buccal wall) no wider than the width of the extracted root.

14. Clinical Application of Biocompatible Bone Grafts Treating extraction sites for incisors or bicuspids that have completely blown out buccal wall wider than the width of the extracted root.

15. Clinical Application of Biocompatible Bone Grafts Treating extraction sites of incisors or bicuspids that have lost both buccal and lingual walls no wider than the root.

16. Clinical Application of Biocompatible Bone Grafts Treating extraction sites of molars with a wall missing.

17. Clinical Application of Biocompatible Bone Grafts Treating extraction sites of maxillary teeth with low sinus.

18. Clinical Application of Biocompatible Bone Grafts Treating extraction sites with an apical fenestration.

19. Clinical Application of Biocompatible Bone Grafts Treating extraction sites with an apical fenestration and immediate implants.

20. Clinical Application of Biocompatible Bone Grafts Treating extraction sites with extensive infection and extensive bone loss.

21. Clinical Application of Biocompatible Bone Grafts Sinus Augmentation

22. Clinical Application of Biocompatible Bone Grafts Ridge Augmentation