1. Do Now British Royal Family Pedigree Explain this chart

2. Homework Due for today – Chapter 14, section 1 pages 392-397 (Human Chromosomes) Due Thursday (Wednesday for F Period) - Chapter 14, section 2 pages 398- 401

3. Review Mendel Realized that he could predict how plants would turn out through the use of “Probability.” Not always 100% certain, it was fairly accurate for guessing the outcomes (not taking into account mutations (Progeria for example) or outside forces (rain, fire,….) Mendel used the Law of Segregation to predict outcomes. He created Punnet Square

4. New Material 1. Explain the Law of Segregation. 2. A farmer is frustrated by the fact that he keeps trying to have boys to maintain the farm and eventually take over the farm, but the farmer and his wife keep having girls. They arrive in your office since you are a world renowned geneticists. Through the use of the Law of Segregation, explain to this couple who is responsible for the having boys as well as girls in a marriage. Create a Monohybrid Punnett Square

5. New Material 3. Explain the Principle of Dominance 4. Using the examples below circle the phenotypes. 5. Using the examples write out all the homozygous traits 6. Using the examples write out all the heterozygous traits Tall – TTBrown Hair – BB Tall – TtBrown Hair – Bb Short – ttBlonde Hair – bb Green Eyes – GG Green Eyes – Gg Blue Eyes – bb

6. New Material Principle of Dominance: Some alleles are dominant – meaning Always expressed Some alleles are recessive – meaning they may express the trait unless matched with a dominate allele. But the recessive allele (traits) will be passed from parent cell to offspring.

7. Punnett Squares Phenotype – Physical Trait (Tall) Genotype – genetic make up (arrangement) (TT or Tt) Punnet Squares – mathematical formula to determine outcomes. 4 Box vs. 16 Boxes 4 Box means that we are dealing with one trait. Known as monohybrid (hybrid means a use of two different things) 16 Boxes means it is dealing with two different traits (hair color & eye color for example)

8. New material Below is monohybrid – why? Only one trait - Tall

9. New material Only one trait – Height (Tt X tt) Work it out the probabilities Tt t t

10. New material Only one trait – Height (Tt X Tt ) What are the possible outcomes? If these parents had four kids, how many would be short?

11. Review Mendel used the Law of Segregation to predict outcomes. For example parents with the traits of T= Tall, t= Short, so if two parents had kids we would expect that of there is a 25% chance of having a short child. Often predicted that 1 and 4 chance of having a short child, but is that true? Explain

12. New Material Now do a Punnet Square – Mom’s traits (tt) & dad’s traits (tt). Can only do one trait at a time. In this case mom is short and dad is short (both parents are Homozygous).

13. Dihybrid Di-hybrid – deals with two traits. (p. 316) – each box will have 4 alleles = BbTt X BbTt. B- Brown Hair, b – Red Hair, T – Tall, t – Short

14. Dihybrid Do the following - BbTt X BbTt. B- Brown Hair, b – Red Hair, T – Tall, t – Short BTbTBtbt BT bT Bt bt

15. Ratios How many Brown Hair and Tall will you have? How many Brown Hair & short How many Red Hair & Tall How many Red Hair & short

16. The Master Race Explain Hitler’s “Master Race” Blonde Hair & Blue Eyes. Blonde hair – Is it dominant or a recessive trait? Answer – Recessive (BB or Bb would be dominant). Blue eyes - Is it dominant or a recessive trait? Answer – Recessive (GG or Gg would be dominant). Are they heterozygous or Homozygous? Why is this considered to be more pure? Because it can only be Blonde & Blue eyes because bbgg (Homozygous), unlike BB/Bb & GG/Gg (which could be homozygous or heterozygous)

17. Hitler’s Master Race Explain Hitler’s “Master Race” How would you set up a Punnett Square for this meaning what are the phenotypes and genotypes? Phenotypes – Blonde Hair & Blue Eyes Genotypes – bb (Blonde Hair) & gg (Blue Eyes) for Mom and the same for dad: bbgg & bbgg

18. Do the following Create the genotype formula for Hitler’s Master Race

19. For the Master Race Do the following – Blonde Hair & Blues eyes mom & dad bbgg for mom and bbgg for dad. No dominants bg bg bg bg bg

20. Do the following Do the following - BbGg X BbGg. B- Brown Hair, b – blonde hair, G – green eyes, g – blue eyes

21. Do the following Do the following - BbGg X BbGg. B- Brown Hair, b – blonde hair, G – green eyes, g – blue eyes BGbGBgbg BG bGBb Bg bg BBGGBbGGBBGgBbGg

22. Review Henry VIII wants a boy. With the use of the Punnett Square his chances of getting a boy or a girl. Use the appropriate genotypes for male / female.