1. The six ingredients of a 20 year international research collaboration John Newnham School of Women’s and Infants’ Health

2. Rule Number 1 Have a good idea, or two

3. Aim: To develop a large cohort of Western Australian children studied from 18 weeks’ gestation to ascertain the relative contributions of familial risk factors, fetal growth, placental development and environmental insults to outcome in infancy and to the precursors of adult morbidity

4. The Raine Study 1989 – 2010 2868 children External funding >$15.3million 121 C1 publications 67 investigators in 18 research groups >72,000 phenotypic data 2.5million SNPs; 100,000 copy number variants 30,000 biological samples Publications

5. The Raine Study team, 2008

6. Original Aim: To apply the 200 year knowledge of sheep handling in Australia to medical research, using minimally invasive ultrasound guided procedures to replace/or complement traditional surgical approaches The SWIH International Perinatal Sheep Research Collaboration 1990-2010 ongoing

7. The SWIH International Perinatal Sheep Collaboration 20 years continuous funding from NIH (plus NHMRC and others) External funding >$7 million 80+ C1 publications >300 conference presentations Extensive knowledge transfer Collaborators from USA, Canada, UK, Japan, Germany, Netherlands, China, Malaysia, New Zealand and Eastern Australia

8. The international sheep research group, 2008

9. Rule Number 2 Successful research teams are based on mutual benefit and friendship

10. Rule Number 3 We are all different. Not everyone is suited to be in longstanding team

11. Rule Number 4 Each member/group in the collaboration needs their own sovereignty

12. Rule Number 5 If in doubt: Achieve the objective, Maintain the group, Care for personal needs

13. Rule Number 6 The research group that celebrates together, produces together

14. Celebrations: Annual scientific days and dinners Logos Annual T-shirts/stubbie holders/hats Inclusive of family members