1. Office for Responsible Research Dr. Kerry Agnitsch IRB Co-Chair

2. ORR Mission The Office for Responsible Research (ORR) provides administrative services and leadership for ISU’s research compliance program. The ORR’s mission is to assist the Vice President for Research in providing a research environment that fosters honesty, integrity, and a sense of community.

3. Compliance Program Overview ▫Ethics/compliance approvals  Human research (IRB)  Animal research (IACUC)  Research involving biohazards (IBC)  Research involving radiation or radiation producing devices (RSC) ▫Conflicts of Interest ▫Export Controls ▫Responsible Conduct of Research Training

4. Compliance Committee Approval Basics Obtain appropriate approvals BEFORE beginning research activities ▫Forms and information about approval processes can be found on the ORR website ▫Training for PIs and research staff is required Strictly adhere to approved protocols If changes are needed, obtain approval before implementation Continuing review at intervals established by the committee

5. Compliance Committee Approval Basics (cont.) Report any problems, adverse events, deviations from an approved protocol, etc. Allow adequate time for approval We are here to help! Call or stop in if you have questions.

6. Responsible Conduct of Research Training Required for projects funded by NIH, NSF, and USDA- NIFA Requirements for who must be trained and format of training vary by funding agency ▫NSF – undergraduates, graduate students, and post-docs ▫NIH – all individuals receiving support from NIH training, career development awards, research education grants, or dissertation research grants (or any others, if noted in funding opportunity announcements) ▫USDA-NIFA – program directors, faculty, students (graduate or undergraduate), post-docs, and any staff participating in the project

7. RCR Training Format of Training ▫Online training – allowed for NSF and USDA- NIFA-funded projects ▫Face-to-face training (8 hours) required by NIH  GR ST 565  Departments can create their own – must be approved by ORR

8. Conflicts of Interest Basics Conflicts of Interest -- circumstances where an individual's professional actions or decisions at the university could be influenced by considerations of personal gain, usually of a financial nature, as a result of interests outside his/her university responsibilities Annual COI Disclosure – required for faculty, P&S staff, post-docs, and graduate assistants Managing conflicts ▫Department-level management ▫University-level management – for conflicts involving significant financial interests or management roles in external entities

9. Export Controls Export controls (EC) are United States laws that regulate the transfer of designated items to foreign persons both within and outside of the United States and to other countries. Carefully review agreements, contracts, awards, communication, etc. for language about export controls or restrictions on foreign-national participation. If work is subject to export controls: ▫Export Controlled Technology Management Plan ▫Export Control License from the Federal government

10. Questions? ORR Website: www.compliance.iastate.eduwww.compliance.iastate.edu Phone: 294-1515; email: orrweb@iastate.eduorrweb@iastate.edu IRB – 294-4566 or 294-4215 or IRB@iastate.eduIRB@iastate.edu IACUC – 294-9581 or IACUC@iastate.eduIACUC@iastate.edu IBC – 294-9581 or BPHC@iastate.eduBPHC@iastate.edu RSC – 294-7666 or ekarmst@iastate.eduekarmst@iastate.edu COI – 294-7793 or COI@iastate.eduCOI@iastate.edu Export Controls – 294-7793 or Export@iastate.eduExport@iastate.edu