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Noninvasive Quantification of Human Nucleus Pulposus Pressure with Use of T1ρ-Weighted Magnetic Resonance Imaging by An M. Nguyen, Wade Johannessen, Jonathon.

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Presentation on theme: "Noninvasive Quantification of Human Nucleus Pulposus Pressure with Use of T1ρ-Weighted Magnetic Resonance Imaging by An M. Nguyen, Wade Johannessen, Jonathon."— Presentation transcript:

1 Noninvasive Quantification of Human Nucleus Pulposus Pressure with Use of T1ρ-Weighted Magnetic Resonance Imaging by An M. Nguyen, Wade Johannessen, Jonathon H. Yoder, Andrew J. Wheaton, Edward J. Vresilovic, Arijitt Borthakur, and Dawn M. Elliott J Bone Joint Surg Am Volume 90(4):796-802 April 1, 2008 ©2008 by The Journal of Bone and Joint Surgery, Inc.

2 Representative T2-weighted (left) and T1ρ-weighted (right) images of the spine of a fifteen-year- old male donor. An M. Nguyen et al. J Bone Joint Surg Am 2008;90:796-802 ©2008 by The Journal of Bone and Joint Surgery, Inc.

3 Correlation between T1ρ relaxation time and degenerative grade (A) and between T1ρ relaxation time and age (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90:796-802 ©2008 by The Journal of Bone and Joint Surgery, Inc.

4 Comparison of T1ρ relaxation time (A), swelling pressure (Psw) (B), and sulfated- glycosaminoglycan content (s-GAG) per dry weight between non-degenerated and degenerated discs (C). An M. Nguyen et al. J Bone Joint Surg Am 2008;90:796-802 ©2008 by The Journal of Bone and Joint Surgery, Inc.

5 Correlation between T1ρ relaxation time and swelling pressure (Psw) (A) and between swelling pressure and sulfated-glycosaminoglycan content (s-GAG) per dry weight (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90:796-802 ©2008 by The Journal of Bone and Joint Surgery, Inc.

6 Correlation between T1ρ relaxation time and sulfated-glycosaminoglycan content (s-GAG) per dry weight (A) and between T1ρ relaxation time and water content (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90:796-802 ©2008 by The Journal of Bone and Joint Surgery, Inc.


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