1. Hormones produced by other Major organs Kelly Diaz 3/4/14 A&P

2. Prostaglandins (PGs) This includes several groups indicated by the letters A-I (PGA-PGI) The chemical composition is derived form the fatty acid molecules Source: the plasma membranes of virtually all body cells stimulus is various (local, irritation, hormones, ect.) This hormone has many targets, but only acts locally at site of release Ex. - cause constriction of the respiratory passages ways - stimulate the muscles of the uterus and promote labor - promote inflammation and pain

4. Gastrin The chemical composition is a peptide Source: the stomach To stimulate the hormone is food The target is the stomach: inhibiting glands to release hydrochloric acid (HCI)

5. Intestinal Gastrin Its is a peptide The source is duodenum of the small intestine The stimulus is food, especially fats The target is the stomach and it inhibits HCI secretion and gastrointestinal tract mobility

6. Secretin It’s a peptide the source: duodenum The stimulus is food The target organs are the pancreas which stimulates the bicarbonate-rich juice The liver: increases release of bile The stomach: reduce secretions

7. Cholecystokinin (CCK) It’s a peptide Source: duodenum The stimulus is food The organs it affects are the pancreas which stimulates the enzyme-rich juice Gallbladder: stimulates expulsion of stored bile Duodenal papilla: causes the sphincter to relax, allowing the bile and pancreatic juice to enter the duodenum

8. Erythropoietin The chemical composition is glycoprotein The source is the kidney The stimulus is the hypoxia The target is the bone marrow and they stimulate production of red blood cells

9. Active vitamin D 3 It’s a steroid The source is the kidney(activates the provitamin D made by epidermal cells) The stimulus is PTH The target organ is the intestine stimulating active transport of dietary calcium across intestinal cell membranes

10. Atrial natriuretic peptide (ANP) It’s a peptide The source is the heart The stimulus is the stretching of atria of the heart The target organs are kidney which inhibits sodium ion reabsorption and renin release Adrenal cortex: inhibits secretion of aldosterone and that decreases blood pressure and volume

11. Leptin It’s a peptide Source: Adipose tissue The stimulus is fatty foods The target organ is the brain which suppresses appetite and increase energy expenditure

12. Resistin It’s a peptide The source adipose tissue It doesn’t have a known stimulus The targets are fat, muscle, liver: antagonizes insulin’s action on liver cells

13. Credits Elaine N. Marieb- Essentials of Human Anatomy and Physiology