1. PATHOPHYSIOLOGY OF TRANSPOSITION OF THE ARTERIES (TGA)

2. Systemic Circulation Pulmonary Circulation NORMAL CIRCULATION Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle PULMONARY ARTERY Pulmonary Vein Left Atrium Left Ventricle AORTA Vena Cava

3. Systemic Circulation TGA CIRCULATION Pulmonary Circulation Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle AORTA Pulmonary Vein Left Atrium Left Ventricle PULMONARY ARTERY Vena Cava RV LV

4. TGA CIRCULATION Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle AORTA Pulmonary Vein Left Atrium Left Ventricle PULMONARY ARTERY Vena Cava INCOMPATIBLE WITH LIFE!!! TWO SEPARATE CIRCULATIONS UNLESS… INCOMPATIBLE WITH LIFE!!! HYPOXIA

5. TGA CIRCULATION Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle AORTA Pulmonary Vein Left Atrium Left Ventricle PULMONARY ARTERY Vena Cava ATRIAL SEPTAL DEFECT PATENT DUCTUS ARTERIOSIS VENTRICULAR SEPTAL DEFECT

6. PHYSIOLOGY BEHIND TRICUSPID VALVE REGURGITATION

7. HIGH PRESSURE LOW PRESSURE HIGH PRESSURE LOW PRESSURE NORMAL CIRCULATION Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle PULMONARY ARTERY Pulmonary Vein Left Atrium Left Ventricle AORTA Vena Cava Systemic Circulation Pulmonary Circulation Right Atrium Right Ventricle AORTA Pulmonary Vein Left Atrium Left Ventricle PULMONARY ARTERY Vena Cava Tricuspid Valve TGA CIRCULATION