12Complications of LPSquamous cell carcinoma in oral ulcerative lesions.Cicatricial alopecia in scalp LP.Postinflammatory hyperpigmentation.
13Treatment No cure but we can use: Medicines used to treat lichen planus include:Oral and topical steroidOral retinoidimmunosuppressant medicationsHydroxychloroquinTacrolimusDopson
14Chicken PoxOccurs primarily in children, although adults who are not immune can contract it.It is quite contagious and is spread by breathing in infected respiratory droplets or unprotected direct contact with the rash when it has ruptured.In person’s who have had chickenpox, the virus can cause shingles later in life.
15Clinical presentation The best known symptom of chickenpox is the itchy, red rash that breaks out on the face, scalp, chest, back, and sometimes arms and legs.The rash usually appears about 2 weeks after exposure to the virus and begins as superficial spots.The spots quickly fill with a clear fluid(vesicles), rupture, and turn crusty.The scabs then fall off in a week or two.
16The rash continues to break out for the first 1 to 5 days, so spots at various stages of development may be present at the same time.A secondary infection of the ruptured rash by bacteria may cause high fever and skin scarring.
20Treatment Isolate the diseased until the rash crusts. Cool, wet compresses , calamine lotion , antihistamines help to relieve itching.Complications are treated according to symptoms; Secondary bacterial pneumonia is treated with antibiotics.Acyclovir is used for severe varicella infections involving the lungs or the brain and in persons with a depressed immune system.
21Human Papillomavirus (HPV): WARTS Warts are caused by HPVHPV infects skin and mucosal epitheliaInfection causes hyperplasia of the epithelium = a wartHPV infects the basal keratinocytes of cutaneous and mucosal epithelium21
22Epidemiology One of the top three skin problems in children Peak prevalence is during adolescence (13-16 years old)about 5-20% of teens are affectedMales and females are equally affected
23Role of HPV in Cutaneous Disease HPV can be transmitted by skin-to- skin contact or through contaminated surfaces or objectsPatients can also spread virus from a wart to unaffected skin
25Clinical Features of Verruca Vulgaris Hyperkeratotic,dome-shaped papules or nodulesMost common on fingers, dorsal hands, knees or elbows but may occur anywhereMay koebnerize – spread with skin trauma
26Clinical Features of Verrucae Planae: Flat Warts Skin-colored or pinkSmooth-surfaced, slightly elevated, flat-topped papulesDorsal hands, arms, face (exposed surfaces)
27Clinical Features of Palmoplantar Verruca Thick, endophytic (depressed into skin of sole) papulesMosaic warts: plantar warts coalescing into large plaques
28First Line Approaches to Wart Treatment Cryotherapy – liquid nitrogenSalicylic acid – chemically irritating, destructiveOther therapies that may be used include:Laser: pulse dye laser