1. 第廿八次護理研究論文發表會暨兩岸護理學術交流 The Comparative Efficacies of Airway Clearance Techniques and Pursed-Lip Breathing in Hospitalized Patients With Acute COPD Exacerbation Lin-Yu Laio1, Kuei-Min Chen2, Jung-Yien Chien3 Chest Hospital, Department of Health Executive Yuan1,3 Ph.D. Student, Kaohsiung Medical University 1 Professor, Kaohsiung Medical University 2 Background ： The role of respiratory tract cleansing and pursed-lip breathing in patients with COPD AE is still on clear. Purpose: Acute exacerbation of COPD, potentially due to gas change, often increases mucus production and dyspnea (Burge & Wedzicha, 2003). Airway clearance techniques and pursed-lip breathing have been used to help reduce sputum and improve dyspnea in patients with COPD AE. This study tested the effects of airway clearance techniques and pursed-lip breathing rehabilitation program in patients with COPD AE. Table 1. Demographic profiles N=53 Table 2. Dyspnea Scales Analysis TimeM±SDtp Admitted 1 st and 2 rd 3.92.001 *** Admitted 1 st 4.45±3.33 Admitted 2 nd 3.38±3.11 Admitted 1 st and 3 rd 5.90.001 *** Admitted 1 st 4.45±3.33 Admitted 3 rd 2.43±2.58 Admitted 1 st and 4 th 7.31.001 *** Admitted 1 st 4.45±3.33 Admitted 4 th 1.70±1.97 Admitted 2 rd and 3 rd 4.203.001 *** Admitted 2 nd 3.38±3.11 Admitted 3 rd 2.43±2.58 Admitted 2 rd and 4 th 5.54.001 *** Admitted 2 nd 3.38±3.11 Admitted 4 th 1.70±1.97 Admitted 3 rd and 4 th 4.67.001 *** Admitted 3 rd 2.43±2.58 Admitted 4 th 1.70±1.97 VariableM±SDn(%)Variablen(%) Age66.53±10.18 Education High159.45±7.69 NO15(28.3%) Body Weight58.83±10.62 Primary school27(50.90%) BMI23.25±4.00 Junior school10(18.90%) Peak flow132.08±62.78 High school1(1.9%) Sex Chronic diease Male 35(66.00%)NO8(15.1%) Femal 18(34.00%)Yes45(84.9%) Marry Smoking No 35(66.00%)No 32(60.4%) Yes 18(34.00%)Yes 21(39.6%) Methods : A pre-test and post-test quasi- experimental design was applied; A convenience sample of 53 patients with acute exacerbation of COPD was recruited from a chest hospital in southern Taiwan; Airway clearance techniques and pursed-lip breathing were applied 30 minutes per time on the first day of admission (baseline) and on the 2nd, 3rd, and 4th days (post-tests); Sputum and dyspnea score were measured to measure intervention efficacy (Wu, 2008) Table3 Sputum Scales Analysis Time M±SDtp Admitted 1 st and 2 rd -1.7980.078 Admitted 1 st 1.00±0.81 Admitted 2 nd 1.21±0.69 Admitted 1 st and 3 rd 3.3460.002 Admitted 1 st 1.00±0.81 Admitted 3 rd 1.49±0.64 Admitted 1 st and 4 th 3.8760.00 Admitted 1 st 1.00±0.81 Admitted 4 th 1.53±S0.58 Admitted 2 rd and 3 rd 2.9860.004 Admitted 2 nd 1.21±0.69 Admitted 3 rd 1.49±0.64 Admitted 2 rd and 4 th 2.9070.005 Admitted 2 nd 1.21±0.69 Admitted 4 th 1.53±S0.58 Admitted 3 rd and 4 th 0.4680.642 Admitted 3 rd 1.49±0.64 Admitted 4 th 1.53±S0.58 Implication for Practice: Airway clearance techniques and pursed-lip breathing improve sputum clearance and decrease dyspnea. This article provides guidance to nurses responsible for treating inpatients with acute COPD exacerbation Key Words: Airway Clearance Techniques, Pursed-Lip Breathing, Chronic Obstructive Pulmonary Disease