1. Second line of Defense

2. Inflammation The “inflammatory process” Response to injury such as; cut/burn/scrape/tear/pathogen Non-specific immunity

3. 4 Cardinal Signs Swelling Pain Redness Increased temperature at the sight

4. Process Body becomes injures Histamine (vasodilator is released at the site) Blood vessels dilate Blood flow increases Phagocytes are quickly rushed to the site Pathogens/injured tissue are dismantled

5. Increased Temperature At the site of injury/not systemic Accumulation of warm blood at the site Increases the temperature

6. Redness Accumulation of blood Rises to higher level in tissues See redness Also heat causes redness

7. Swelling Accumulation at site of injury Excess tissue fluids Excess blood supply Pathogens/phagocytes/dead cell parts Development of pus (white)

8. Pain Pressure from excess fluids Press onto nerve endings Throbbing feeling

9. Reducing Symptoms Pain relievers RICE; rest/ice/compression/elevation ? Antibiotic use