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Mechanism of capping (viral capping enzyme)

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Presentation on theme: "Mechanism of capping (viral capping enzyme)"— Presentation transcript:

1 Mechanism of capping (viral capping enzyme)
PP-RNA + GMP G-PPP-RNA Hakansson et al et Wigley, Cell 1997

2 CBP20-m7GpppG contacts

3 Alternative-splicing of the DSCAM gene
Can produce up to different protein isoforms From Black D.L. Cell (2000), v103 p367

4 Pre-mRNA editing by Adenosine deamination
Human genes Drosophila genes From Reenan Trends in Genetics (2001), v17 p53

5 Pumilio domain (Wang et al, Cell, 2002)

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8 dsRBD-RNA Ryter and Schultz, Embo J, 1998

9 Zinc finger-RNA (Lu et al, Nature , 2003)

10 Zinc finger4-DNA Zinc finger4-RNA (Nolte et al, PNAS , 1998)
(Lu et al, Nature , 2003)


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