1. A Continuity Equation Based Optical Flow Method for Cardiac Motion Correction in 3D PET Data M Dawood, C Brune, X Jiang, F Büther, M Burger, O Schober, M Schäfers, KP Schäfers Department of Computer Science, European Institute for Molecular Imaging University of Münster, Germany

2. 2 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Coincidence Unit Sorting Unit Image Reconstruction PET Image Detectors Decay Millions of events are detected during few minutes of PET scan Positron Emission Tomography

3. 3 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms PETCT Problem: Motion artifacts PET/CT

4. 4 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms PET, Minutes CT, Seconds Acquisition Times

5. 5 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms … Gating

6. 6 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Mass conserved in cardiac data SystoleDiastole Continuity Equation:

7. 7 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Motion vectors

8. 8 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms All gates deformed to Diastole Visual results Cardiac phases

9. 9 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Quantitative results 1: Correlation with target phase

10. 10 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Quantitative results 2: Myocardial thickness

11. 11 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Quantitative results 3: Time activity curves in blood pool

12. 12 European Institute of Molecular Imaging Motion Correction on 3D PET/CT Data with Optical Flow Algorithms Thank you