1. Once Weekly Spaced Retrieval Training can Lead to Learning in People with Dementia. Chris Materne, Mary Luszcz & Malcolm Bond

2. Conflict of Interest Disclosure Chris Materne, B Psych (Hons) Mary, Luszcz, PhD Malcolm Bond, PhD Have no real or apparent conflicts of interest to report.

3. Rationale Need exists for a range of nonpharmacological options in response to increasing incidence of dementia Spaced retrieval has demonstrated effectiveness when delivered intensively and with individuals with moderate to severe dementia

4. Aims of Study Assess effectiveness of spaced retrieval training delivered once per week in community dwelling individuals Identify if any long term benefits Ascertain relationship of spaced retrieval training effectiveness with range of cognitive measures

5. Spaced Retrieval Practise at successfully recalling information over progressively longer intervals Ultimate goal - ability to recall information and/or use skills over clinically meaningful periods of time

6. Baseline characteristics Characteristic (n = 14)Mean (SD) Age (yrs)81.64 (5.98) Education (yrs)11.00 (2.63) Estimated IQ (from NART errors) 105.41 (9.09) MMSE19.79 (7.25) RBANS Total Index60.64 (15.15) RBANS Attention Index 85.07 (24.71) RBMT Adjusted Profile Score Total1.14 (2.45) TMT–A (secs)(n=13)98.77 (69.12) DSS (# symbols in 120 secs)(n=11)27.46 (11.03)

7. Baseline Characteristics Number : Number Women : Men10 : 4 Living with Family member : Alone10 : 4 Participant Partner – Spouse: Daughter : Son : Sibling7 : 5 : 1 : 1 AD : FTD : Non Specific Dementia10 : 1 : 3 Self Rated Health – Ave : Good : Very Good5 : 7 : 1 Dementia Related Medication6

8. Sidney Male 81 years old 15 years education MMSE = 13 Recall Prompt Use Info/strategy post –interventionYes 3 month follow upYes 6 month follow upYes

9. Ruth Female 94 years old 11 years education MMSE = 19 Recall Prompt Use Info/strategy post –interventionNo 3 month follow upNo 6 month follow upN/A

10. April Female 88 Years old 10 years education MMSE = 25 Recall Prompt Use Info/strategy post –interventionYes 3 month follow upNoYes 6 month follow upNoYes

11. Spaced Retrieval Training Retention Post- intervention 3 Month Follow up 6 Month Follow up Correct, using strategy1275 Correct, not using strategy--- Incorrect, using strategy-22 Incorrect, not using strategy133 Strategy no longer appropriate-13 Entries show number per category

12. Spaced Retrieval: Correlations with Performance RBANS (Tot) # Trials to 20 min recall # Trials to 1 week recall MMSE.891**-.599*-.528 RBANS (Tot)-.537-.468 RBANS (Attn).886**-.576*-.488 TMT-.696**.387.233 DSS.606*-.165-.061 RBMT.651*-.691**-.676* * = p <.05, ** = p <.001

13. Conclusions Spaced retrieval training generally well tolerated by people in early & moderate stages of dementia Appears to be effective form of memory training when delivered weekly to achieve a variety of goals Appears to be fairly robust post-training, with scope to enhance retention