1. Orange Team Ryan Null Project Manager CS 410 Orange Team 10 December, 2008 1 Old Dominion University: Computer Science CS 410 Orange Team - HEART

2. Team Orange Professor Brunelle David Hardware Specialist Ryan Project Manager Andrew Finance and Webmaster Spencer Software and Market Nicole Software Specialist Generoso Systems Specialist Experts Dr. Daniel Garland M.D. President of Pathologist Department Obici Hospital Suffolk Mrs. Janet Jackson BSN RN HCMSDM Regulatory Compliance Manager Amerigroup Corporation Virginia Beach 10 December, 20082 Old Dominion University: Computer Science CS 410 Orange Team - HEART

3. Cardiac Rehabilitation Retention Cardiac patients do not commit to the long-term rehabilitation necessary to extend their life. 10 December, 20083 Old Dominion University: Computer Science CS 410 Orange Team - HEART

4. Societal Cost of Cardiac Failure The direct and indirect cost to the U. S. in 2008 alone are staggering. [1] $156.4 billion for Cardiac Heart Disease $448.5 billion for Cardio Vascular Disease [1] http://www.americanheart.org/presenter.jhtml?identifier=3050603 10 December, 20084 Old Dominion University: Computer Science CS 410 Orange Team - HEART

5. Need for Cardiac Rehabilitation Is Increasing 22 million people experience heart failure every year [1] 5 million people in the United States are living with a heart condition [2] 500, 000 additional cases are diagnosed each year [1] Popular Science Magazine, December 2008, 61 - 63 [2] http://www.americanheart.org/presenter.jhtml?identifier=3047844 10 December, 20085 Old Dominion University: Computer Science CS 410 Orange Team - HEART

6. 80% of Patients Cease Cardiac Rehabilitation Team Orange SBIR page 9 10 December, 20086 Old Dominion University: Computer Science CS 410 Orange Team - HEART

7. Rehabilitation Exercises Extend Life Doctor prescribed exercises are essential to successful rehabilitation. [1] Increased heart strength and mobility Lower blood pressure, cholesterol, and BMI Reduced emotional stress, depression, and anxiety [1] http://www.mayoclinic.com/health/cardiac-rehabilitation/HB00017 10 December, 20087 Old Dominion University: Computer Science CS 410 Orange Team - HEART

8. Challenges to Monitoring Cardiac Patient Exercise Team Orange SBIR Appendix J 10 December, 20088 Old Dominion University: Computer Science CS 410 Orange Team - HEART

9. Tools to Encourage Rehabilitation Are Needed According to Dr. Suaya “We need to find ways to increase the use of cardiac rehabilitation, because it is used very little by patients who could benefit a lot…” [1] The A.H.A. “recommends physicians aggressively encourage cardiac rehabilitation…” [1] http://www.americanheart.org/presenter.jhtml?identifier=3050603 10 December, 20089 Old Dominion University: Computer Science CS 410 Orange Team - HEART

10. Patient Involvement Is Key to Rehabilitation According to Beaumont Hospitals “Active involvement of the patient and family is vital to the success of the program.” [1] And ABC reports “[…] If the patient is actively engaged […] they feel like they have some control over what they will do and how they will do it.” [2] [1] https://www.beaumonthospitals.com/health-library/P06321 [2] http://www.abc.net.au/rn/healthreport/stories/2007/2023663.htm 10 December, 200810 Old Dominion University: Computer Science CS 410 Orange Team - HEART

11. Current Rehabilitation System Team Orange SBIR page 11 10 December, 200811 Old Dominion University: Computer Science CS 410 Orange Team - HEART

12. Tools Available for Cardiac Rehabilitation Team Orange SBIR page 16 10 December, 200812 Old Dominion University: Computer Science CS 410 Orange Team - HEART

13. Goals of Cardiac Rehabilitation Retention Solutions Lifestyle Education Increase involvement in rehabilitation process Illustrate concrete benefits of changes through historical data Support Accountability and control of exercise regimen Positive feedback on progress Team Orange SBIR page 9-10 10 December, 200813 Old Dominion University: Computer Science CS 410 Orange Team - HEART

14. H eart E xercise A ccelerometer R ehabilitation T ool Contains mechanics to monitor and record patients’ heart rate, exercise type, intensity, and duration each time they exercise Give feedback to reinforce positive progress with reports and analysis of future potential benefits Be utilized during rehabilitation, home exercises, and patient follow-ups Be non-intrusive and not substantially modify established rehabilitation processes 10 December, 200814 Old Dominion University: Computer Science CS 410 Orange Team - HEART

15. Modified Rehabilitation System Team Orange SBIR page 12 10 December, 200815 Old Dominion University: Computer Science CS 410 Orange Team - HEART

16. H.E.A.R.T. Technical Overview Team Orange SBIR page 13 10 December, 200816 Old Dominion University: Computer Science CS 410 Orange Team - HEART

17. H.E.A.R.T. Cardiac Patient Use Team Orange SBIR page 14 10 December, 200817 Old Dominion University: Computer Science CS 410 Orange Team - HEART

18. Patient and Rehabilitation Software Team Orange SBIR page 13 10 December, 200818 Old Dominion University: Computer Science CS 410 Orange Team - HEART

19. Cardiac Patient Software Report Team Orange SBIR page 13 10 December, 200819 Old Dominion University: Computer Science CS 410 Orange Team - HEART

20. H.E.A.R.T. Limitations The system is not capable of the following Medical diagnosis Exercise prescription Compulsion of proper utilization of the system by the doctor, rehabilitation specialist, and patient Team Orange SBIR Appendix H 10 December, 200820 Old Dominion University: Computer Science CS 410 Orange Team - HEART

21. Required Measurements for Cardiac Rehabilitation Tools Team Orange SBIR Appendix J 10 December, 200821 Old Dominion University: Computer Science CS 410 Orange Team - HEART

22. H.E.A.R.T. Capabilities Team Orange SBIR page 16 10 December, 200822 Old Dominion University: Computer Science CS 410 Orange Team - HEART

23. H.E.A.R.T. Project Management Management Plan Marketing PlanDevelopment Plan Evaluation PlanStaffing Plan Financial PlanWork Breakdown Structure Funding PlanRisk Management Plan 10 December, 200823 Old Dominion University: Computer Science CS 410 Orange Team - HEART

24. H.E.A.R.T. Risk Management Identify and categorize risks according to severity and probability Mitigate the impact of risks by preventing the cause or alleviate current risks Continually re-examine risks throughout all phases Anticipate and be aware of new risks Team Orange SBIR Appendix G 10 December, 200824 Old Dominion University: Computer Science CS 410 Orange Team - HEART

25. H.E.A.R.T. Risk Analysis Probability Not LikelyLowModerateHighExpected Impact ExtremeT1, F1 HighF2C1 ModerateT3C2T2F3 Low Negligible ItemTechnical RisksProbabilityImpact T1Hardware and Software Interoperability25 T2Hardware and Software Accuracy13 T3Malfunction (Device and Software)33 ItemFinancial RisksProbabilityImpact F1FDA Rejection25 F2Insurance Rejection24 F3Market Competition43 ItemCustomer RisksProbabilityImpact C1Rehabilitation Acceptance34 C2Proper Utilization23 10 December, 200825 Old Dominion University: Computer Science CS 410 Orange Team - HEART

26. Phase 0 Organization Team Orange SBIR Appendix C 10 December, 200826 Old Dominion University: Computer Science CS 410 Orange Team - HEART

27. Phase 0 Task List Team Orange SBIR Appendix F 10 December, 200827 Old Dominion University: Computer Science CS 410 Orange Team - HEART

28. Phase 0 Gantt Team Orange SBIR Appendix F 10 December, 200828 Old Dominion University: Computer Science CS 410 Orange Team - HEART

29. Phase 0 Marketing Team Orange SBIR Appendix B 10 December, 200829 Old Dominion University: Computer Science CS 410 Orange Team - HEART

30. Phase 0 Funding Old Dominion University will provide the funding for all necessary resources. Team Orange SBIR Appendix D 10 December, 200830 Old Dominion University: Computer Science CS 410 Orange Team - HEART

31. Phase 0 Evaluation Phase 0 will be a success if it accomplishes the following on schedule WBS Feasibility, Milestone, and Approval Presentation Product Website SBIR Phase 1 Proposal approval Team Orange SBIR Appendix H 10 December, 200831 Old Dominion University: Computer Science CS 410 Orange Team - HEART

32. Phase 1 Organization Team Orange SBIR Appendix C 10 December, 200832 Old Dominion University: Computer Science CS 410 Orange Team - HEART

33. Phase 1 Task List Team Orange SBIR Appendix F 10 December, 200833 Old Dominion University: Computer Science CS 410 Orange Team - HEART

34. Phase 1 Gantt Team Orange SBIR Appendix F 10 December, 200834 Old Dominion University: Computer Science CS 410 Orange Team - HEART

35. Phase 1 Marketing The focus of Marketing in Phase 1 includes the following Secure SBIR grant for Phase 2 Pay down on outstanding notes Generate product demand for Phase 2 Team Orange SBIR Appendix B 10 December, 200835 Old Dominion University: Computer Science CS 410 Orange Team - HEART

36. Phase 1 Hardware Budget HardwareQty Unit Cost Total Heart Rate Monitor2$100.00$200.00 Piezoelectric Accelerometer4$50.00$200.00 Software (QA)1$10.00 Receivers2$10.00$20.00 Transmitters4$10.00$40.00 Production2$10.00$20.00 Material (Box, Paper, assoc, etc)2$10.00$20.00 Assembly and Manufacturing2$30.00$60.00 Memory, Battery, cables, base station4$75.00$300.00 Prototype I1$50,000.00 Prototype II1$18,000.00 Labor and AV technicians2$300.00$600.00 Tax (8.8%) $6,037$6,113 Total Phase 1 Hardware Budget $75,583 Team Orange SBIR Appendix E 10 December, 200836 Old Dominion University: Computer Science CS 410 Orange Team - HEART

37. Phase 1 Staffing Budget TitleQtySalaryHours Hourly RateTotal Project Manager1$31,20070$15$1,050 Software Manager1$31,200460$15$6,900 Hardware Manager1$31,200380$15$5,700 Financial Director1$31,20045$15$675 Marketing Director1$31,20065$15$975 Risk Director1$31,20060$15$900 Documentation Specialist1$31,20055$15$825 Webmaster1$31,20015$15$225 Total Cost$17,025 All employees are Students 40% Overhead$6,810 Phase 1 = 6 month period Total Phase 1 Staffing Budget:$23,835 Phase 1 Total Budget: $99,418 Team Orange SBIR page 29 10 December, 200837 Old Dominion University: Computer Science CS 410 Orange Team - HEART

38. Phase 1 Funding Grants.gov $33,000,000: Research Experiences for Undergraduate Funding $750,000: Cardiac Translational Research Implementation $250,000: Improving Heart Failure Disease Management Small Business Administration $100,000: SBIR Phase 1 Grant Team Orange SBIR Appendix D 10 December, 200838 Old Dominion University: Computer Science CS 410 Orange Team - HEART

39. Phase 1 Evaluation Phase 1 will be a success if it accomplishes the following on schedule Functional H.E.A.R.T. Prototype SBIR Phase 2 Proposal approval Approval from FDA, insurance companies, and rehabilitation centers Team Orange SBIR Appendix H 10 December, 200839 Old Dominion University: Computer Science CS 410 Orange Team - HEART

40. Phase 2 Organization Team Orange SBIR Appendix C 10 December, 200840 Old Dominion University: Computer Science CS 410 Orange Team - HEART

41. Phase 2 Task List Team Orange SBIR Appendix F 10 December, 200841 Old Dominion University: Computer Science CS 410 Orange Team - HEART

42. Phase 2 Gantt Team Orange SBIR Appendix F 10 December, 200842 Old Dominion University: Computer Science CS 410 Orange Team - HEART

43. Phase 2 Break Even Analysis Team Orange SBIR Appendix B 10 December, 200843 Old Dominion University: Computer Science CS 410 Orange Team - HEART

44. Phase 2 Marketing The focus of Marketing in Phase 2 includes the following $150,000 revenue by second year of Phase 2 $180,000 profit Identify new markets and increase market share Team Orange SBIR Appendix B 10 December, 200844 Old Dominion University: Computer Science CS 410 Orange Team - HEART

45. Phase 2 Hardware Budget HardwareQuantityCpUTotal Cost Heart Rate Monitor1,000$45.00$45,000.00 Piezoelectric Accelerometer2,000$15.00$30,000.00 Receivers2,000$5.00$10,000.00 Transmitters2,000$5.00$10,000.00 Production2,000$5.00$10,000.00 Material (Box, Paper, assoc, etc)‏2,000$5.00$10,000.00 Assembly and Manufacturing2,000$10.00$20,000.00 Memory, Battery, cables, base station2,000$30.00$60,000.00 Training45$80.00$3,600.00 Testing100$150.00$15,000.00 Tax (8.8%)‏ $30.80$18,796.80 Total Phase 3 Hardware Budget $137,396.80 Team Orange SBIR Appendix E 10 December, 200845 Old Dominion University: Computer Science CS 410 Orange Team - HEART

46. Phase 2 Staffing Budget TitleQtySalaryHoursHourlyTotal Project Manager1$87,0001200$42$50,192 Software Engineer2$71,0002000$34$136,538 Hardware Engineer2$81,0001800$39$140,192 Financial Director1$62,000420$30$12,519 Marketing Director1$44,000460$21$9,731 Documentation Specialist1$42,000600$20$12,115 HR Manager1$56,000220$27$5,923 Technical Director1$70,000680$34$22,885 Software/Hardware Tester1$69,000450$33$14,928 Webmaster1$40,000160$19$3,077 Total Cost$405,024 All employees are Full Time 40% Overhead$162,010 Phase 2 = 2 year period Total Phase 2 Staffing Budget:$567,034 Phase 2 Total Budget: $704,430 Team Orange SBIR page 29 10 December, 200846 Old Dominion University: Computer Science CS 410 Orange Team - HEART

47. Phase 2 Funding US Small Business Administration SBIR Grants – Up to $750,000 SBIR Loans US Department of Commerce Team Orange SBIR Appendix D 10 December, 200847 Old Dominion University: Computer Science CS 410 Orange Team - HEART

48. Phase 2 Evaluation Phase 2 will be a success if it accomplishes the following on schedule Fully functional H.E.A.R.T. System Production ready prototype Break-Even-Point reached and exceeded Team Orange SBIR Appendix H 10 December, 200848 Old Dominion University: Computer Science CS 410 Orange Team - HEART

49. Phase 3 Organization Team Orange SBIR Appendix C 10 December, 200849 Old Dominion University: Computer Science CS 410 Orange Team - HEART

50. Phase 3 Task List Team Orange SBIR Appendix F 10 December, 200850 Old Dominion University: Computer Science CS 410 Orange Team - HEART

51. Phase 3 Gantt Team Orange SBIR Appendix F 10 December, 200851 Old Dominion University: Computer Science CS 410 Orange Team - HEART

52. Phase 3 Marketing The focus of Marketing in Phase 3 includes the following Analysis of market campaign and market share Customer analysis of retention and refinements Acquire new markets Team Orange SBIR Appendix B 10 December, 200852 Old Dominion University: Computer Science CS 410 Orange Team - HEART

53. Phase 3 Hardware Budget HardwareQtyCpUTotal Cost Heart Rate Monitor1,500$45.00$67,500.00 Piezoelectric Accelerometer3,000$15.00$45,000.00 Receivers3,000$5.00$15,000.00 Transmitters3,000$5.00$15,000.00 Production3,000$5.00$15,000.00 Material (Box, Paper, assoc, etc)‏3,000$5.00$15,000.00 Assembly and Manufacturing3,000$10.00$30,000.00 Memory, Battery, cables, base station3,000$30.00$90,000.00 Training100$80.00$8,000.00 Testing500$150.00$75,000.00 Tax (8.8%)‏ $30.80$33,044.00 Total Phase 2 Hardware Budget $266,044.00 Team Orange SBIR Appendix E 10 December, 200853 Old Dominion University: Computer Science CS 410 Orange Team - HEART

54. Phase 3 Staffing Budget TitleQtySalaryHoursHourlyTotal Project Manager1$87,000600$42$25,096 Software Engineer1$71,0001000$34$34,135 Hardware Engineer1$81,000800$39$31,154 Financial Director1$62,000450$30$13,413 Marketing Director1$44,000500$21$10,577 Documentation Specialist1$42,000400$20$8,077 HR Manager1$56,000170$27$4,577 Technical Director1$70,000440$34$14,808 Software/Hardware Tester1$69,000500$33$16,587 Lawyers1$64,000900$31$27,692 Procurement Manager1$50,000350$24$8,413 Customer Service5$41,000650$20$64,063 Webmaster1$40,000160$19$3,077 Total Cost$258,591 All employees are Full Time 40% Overhead$103,437 Phase 3 = Production Total Phase 3 Staffing Budget:$362,028 Phase 3 Total Budget: $628,072 Team Orange SBIR page 29 10 December, 200854 Old Dominion University: Computer Science CS 410 Orange Team - HEART

55. Budget Overview PhaseStaffingHardwarePhase Total Phase 1 (6 months)‏$23,835$1,599$99,800 Phase 2 (Two Years)‏$567,034$137,397$704,430 Phase 3 (Per Year)‏$362,028$266,044$628,072 Total Phases 1-3$952,897$405,040$1,357,937 Team Orange SBIR page 29 - 31 10 December, 200855 Old Dominion University: Computer Science CS 410 Orange Team - HEART

56. Phase 3: Funding Various Investor Groups: National Venture Capital Association Funding Universe U.S. Angel Investors Vision 2 Reality (v2r.com)‏ Team Orange SBIR Appendix D 10 December, 200856 Old Dominion University: Computer Science CS 410 Orange Team - HEART

57. Phase 3 Evaluation Phase 3 will be a success if it accomplishes the following on schedule A commercially viable H.E.A.R.T. System Acquire new markets and functionality for the H.E.A.R.T. System Team Orange SBIR Appendix H 10 December, 200857 Old Dominion University: Computer Science CS 410 Orange Team - HEART

58. H.E.A.R.T. Conclusion Financial Incentives Generate historical data on exercises and their associated heart rate for scientific study and innovation Reduce health care costs by decreasing future cardiac intervention and hospitalization Return-On-Investment after 866 units sold 10 December, 200858 Old Dominion University: Computer Science CS 410 Orange Team - HEART

59. H.E.A.R.T. Conclusion Cardiac Rehabilitation Patient Incentives The patient will Be involved in managing their rehabilitation through feedback on progress Develop and maintain positive long-term lifestyle changes as recommended by their rehabilitation specialists Be educated and accountable for their long term exercise and rehabilitation regimen 10 December, 200859 Old Dominion University: Computer Science CS 410 Orange Team - HEART