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Review How do parental types differ from recombinants? What are two ways recombinants can be formed?
Caused by physical and chemical disturbances Caused by errors in meiosis Plants tolerate abnormalities better than animals
Nondisjunction results in... Aneuploidy e.g. 2n + 1 and 2n - 1 Polyploidy e.g. 3n and 4n
Chromosome breakage Deletion Duplication Inversion Translocation
Resulting genetic disorders... Down Syndrome (aka trisomy 21) Klinefelter syndrome = XXY XXX Turner syndrome = X0 Cri du chat Cancer
Genetic imprinting A given allele does not ALWAYS have the same phenotypic effect Sometimes it depends on whether the allele was inherited from the male or female parent
Cytoplasmic genes NOT all of a eukaryote's genes are located on nuclear chromosomes Genes are also found in mitochondria and chloroplasts e.g. Electron transport proteins
Lecture #6 Date ________
Alterations of Chromosomes
Chapter 15 The Chromosomal Basis of Inheritance. Fig. 15-2b 0.5 mm Meiosis Metaphase I Anaphase I Metaphase II Gametes LAW OF SEGREGATION The two alleles.
Chapter 15~ The Chromosomal Basis of Inheritance
Chromosomal Theory of Inheritance
Fig The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights the gene.
Errors in mitosis or meiosis can results in changes in phenotype
The Chromosomal Basis of Inheritance Chapter 15. Review Mitosis Meiosis Chromosome Genotype and Phenotype Mendelian Genetics.
The Chromosomal Basis of Inheritance Chapter 15. The importance of chromosomes In 1902, the chromosomal theory of inheritance began to take form, stating:
KARYOTYPE TESTS. KARYOTYPE = Image of all the chromosomes from the nucleus of a cell Can be done to identify genetic disorders.
Chromosomal Basis of Inheritance Chapter 15. Most genetics work done on fruit flies (little time to observe many generations) Thomas Morgan - fruit fly.
A.Rules of probability 1. Rule of multiplication a. how do we determine the chance that two or more independent events will occur together in a specific.
Chapter 15 notes The Chromosomal Basis of Inheritance.
Inheritance Patterns Things that cause alterations in chromosome number or pattern lead to genetic disorders. – Alterations in chromosome number - aneuploidy.
Ch. 15: Chromosomal Abnormalities
AP Biology Errors of Meiosis Chromosomal Abnormalities.
The Chromosomal Basis of Inheritance
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