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NML Bioinformatics Service— Licensed Bioinformatics Tools High-throughput Data Analysis Literature Study Data Mining Functional Genomics Analysis Vector.

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Presentation on theme: "NML Bioinformatics Service— Licensed Bioinformatics Tools High-throughput Data Analysis Literature Study Data Mining Functional Genomics Analysis Vector."— Presentation transcript:

1 NML Bioinformatics Service— Licensed Bioinformatics Tools High-throughput Data Analysis Literature Study Data Mining Functional Genomics Analysis Vector NTI Advance®

2 SoftwareLicense type License number 2008200920102011201220132014 GalaxyOpen AccessUnlimited 1524 Partek FlowAnnual/Floating6 4268 NextbioAnnual/SiteUnlimited 230278318333 BIOBASEAnnual/SiteUnlimited 154226289316 Oncomine*Annual/Named1 40535663 Golden Helix SVS 7**Annual/Floating1 71824 GenevestigatorAnnual/Named10 17192128 Partek Genomics SuiteAnnual/Floating26178101137165204225 Ingenuity Pathway AnalysisAnnual/Floating3102131243308401498553 Vector NTI AdvancePerpetual/Floating2 33677988103115 Total Annual Registered Users 163242411972124815701725 * Oncomine was downsized to 2 named users starting FY2014, user growth in 2014 represent the number of consultation requests ** Golden Helix SVS 7 was downsized from 1 floating license to 1 fixed license starting FY2014 and discontinued in FY2015 Cumulative Annual Registered Users of NML Licensed Commercial Bioinformatics Resources

3 $65,000 $1,870,000 Centralized Licensing Model Delivers Dramatic Cost Saving

4 Average monthly sessions = 314 Average monthly hours = 323 hr Ingenuity Pathway Analysis Usage @ USC (Jan. 2012-Dec.2014)

5 Average monthly denied sessions = 117 Ingenuity Pathway Analysis Monthly Denied Sessions (Jan. 2013-Nov. 2014)

6 Bioinformatics Computing Resources at Norris Medical Library Computer Workstations in Norris Medical Library Hardware: Four Dell Precision T3550/T3660 workstations with 6-core Intel Xeon processors, 24- 32GB memory Software: Partek Flow, Galaxy, Cistrome, annovar R& Bioconductor, CAP-miRSeq Total Storage: 62 TB (May 2015) Custom Computing Cluster in USC High- Performance Computing Hardware: One head node and 9 worker nodes*. Each with dual processor 6/8-core AMD Opteron 6176 or Intel E5-2650, 48-64 GB memory. Software: Partek Flow, Galaxy, Cistrome, R& Bioconductor Total Storage: 4 TB You HPC file system File transfer Log on HPC HPC-NML custom condo Submit jobs HPC-NML head node

7 2014 Next Generation Sequencing (NGS) Data Analysis at NML Bioinformatics Service Galaxy FromTo# Users# Projects# Data Files Total Raw File Size (GB) Estimated Run Time (day) 1/1/201412/31/2014103033845438 Partek Flow FromTo# Users# Projects# Data Files Total Raw File Size (GB) Total Run Time (day) 1/1/201412/31/2014 4623626089901549.5

8 NGS Growth in Biomedical Research

9 Computing Storage Growth at NML Bioinformatics Service


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