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Upper Gastrointestinal Cancer The Triumvirate Mr John P Griffith Consultant Gastrointestinal Surgeon

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The triumvirate Their incidence (per 100 000) OesophagusM 14F 9 StomachM 24.3F 14 Pancreas12 Locally –oesophagus52(1/3) –stomach102(1/2) –pancreas54(1/20)

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The triumvirate Changes in incidence OesophagusAdenoCA of cardia increasing Gastric Falling (proximal migration) PancreasStatic

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Risk factors Agemajority > 70 years Alcoholindependent and synergistic Tobacco Diet Reflux>5 years(not reduced by PPI) Barretts oesophagus

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Outcome 1 & 5 year survival rates Oesophagus27% 9% Stomach28%12% Pancreas12% 3%

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