31 (2) Immunological Diagnosis: Specific serologic tests: Direct Agglutination Test (DAT), ELISA, IFATSkin test (leishmanin test) for survey of populations and follow-up after treatment.Non specific detection of hypergammaglobulinaem by formaldehyde (formol-gel) test or by electrophoresis.
42 Pathology and clinical picture Skin stage: chancre.Haematolymphatic stage: generalized lymphadenopathy, anaemia, generalized organ involvement.Central nervous system stage (CNS): Meningoencephalitis.(Development of the disease more rapid in Trypanosoma brucei rhodesiense)
59 Trichomonas vaginalis Transmission:sexual intercoursecontact with contaminated objects.
60 Trichomoniasis Pathology Female: vaginitis, profuse thin yellowish discharge with bad smellMale:invasion of urethra, prostate and seminal vesicles, causing urethritis but mostly asymptomatic.
61 Signs and Symptoms of Trichomoniasis in Women Sign/SymptomPercent of PatientsAsymptomatic≤ 50%Vaginal/vulvar erythema (redness)75%Frothy, yellow/green discharge25%Vulvar itching20-50%Strawberry cervix< 2%Vaginal odor60%pH > 560-90%Dyspareunia (pain during sexual intercourse)< 25%Dysuria (pain during urination)
62 Signs and Symptoms of Trichomoniasis in Men Sign/Symptom% of PatientsAsymptomatic> 50%Urethral discharge65-100%Pruritus (itching)98.5%Dysuria (pain during urination)5.5%
63 Trichomoniasis Diagnosis Identification of parasite by microscopy of discharge.Examination of vaginal or urethral discharge for T. vaginalis