1. In The Name of God The Merciful

2. Transporting Infectious Substances Dr. Rana Amini Dr. Rana Amini Reference Health Laboratory

4. Sender Receiver Environment General Population Carrier

5. Shipper Safety is your responsibility, today more than ever!

6. The Basis ProperProper PackagingPackaging PackingPacking LabelingLabeling MarkingMarking DocumentationDocumentation Highest level of Safety in Transportation The needed speed in Transportation Highest level of Protection

7. UN model regulationsUN model regulations ICAOICAO IATAIATA WHOWHO National restrictions and regulationsNational restrictions and regulations

8. Mode of transport Air (The most restrict)Air (The most restrict) RailRail RoadRoad MarineMarine

9. Road Local surface transportLocal surface transport Transport of specimen fromTransport of specimen from doctor’s office to lab doctor’s office to lab Hospital to diagnostic labHospital to diagnostic lab One lab to anotherOne lab to another Countries are encouraged to adopt the provisional UN model regulations In all National legislations for road transport.

10. Principle The principle of transport is that the material should not have any possibility of escaping from the package under normal conditions of transport.The principle of transport is that the material should not have any possibility of escaping from the package under normal conditions of transport.

11. Hazard Classes 1)Explosives 2)Gases 3)Flammable Liquids 4)Flammable solids 5)Oxidizing Substances 6)Toxic and infectious substances and organic peroxide 1)Division 6.1-Toxic substances 2)Division 6.2-Infectious substances 7)Radioactive Material 8)Corrosives 9)Miscellaneous

12. Infectious substance Are substances which are known or are reasonably expected to contain pathogens.Are substances which are known or are reasonably expected to contain pathogens. Pathogens are : defined as microorganisms( including bacteria, viruses, rickettsiae, parasites, fungi) and even prions.Pathogens are : defined as microorganisms( including bacteria, viruses, rickettsiae, parasites, fungi) and even prions.

13. Exceptions: Dried blood spot, collected by applying a drop of blood onto absorbent materialDried blood spot, collected by applying a drop of blood onto absorbent material Faecal occult blood screening testFaecal occult blood screening test Blood or blood components to be used for transfusionBlood or blood components to be used for transfusion Tissue or organs to be used for transplantationTissue or organs to be used for transplantation Neutralized or inactivated pathogensNeutralized or inactivated pathogens Non-pathogen microorganismsNon-pathogen microorganisms …

16. Basic triple Packaging System

18. Primary ReceptaclePrimary Receptacle Secondary PackagingSecondary Packaging Outer PackagingOuter Packaging

19. Primary Receptacles Must be water –tight (leak proof). Glass, metal or plastic.Must be water –tight (leak proof). Glass, metal or plastic. A water-tight, leak proof seal must be used, caps must be secured by means such as paraffin sealing tapeA water-tight, leak proof seal must be used, caps must be secured by means such as paraffin sealing tape Note: for lyophilized substances either flame sealed glass ampoules or rubber- stoppered glass vials with metal sealNote: for lyophilized substances either flame sealed glass ampoules or rubber- stoppered glass vials with metal seal

20. Secondary Packaging Water-tightWater-tight Contain sufficient absorbent material to absorb the entire contentContain sufficient absorbent material to absorb the entire content Multiple primary receptacles may either be wrapped individually or separated to prevent conatct between the conatiners.Multiple primary receptacles may either be wrapped individually or separated to prevent conatct between the conatiners.

21. Outer Packaging Must be rigidMust be rigid Withstand several specific testsWithstand several specific tests Resistant to waterResistant to water

23. Marking and labeling DurableDurable On the external surfaceOn the external surface Readily visibleReadily visible Able to withstand weather exposureAble to withstand weather exposure Proper name, address and telephone of the shipperProper name, address and telephone of the shipper

28. Training Familiarization Job specific

29. www.iata.org

31. Bio-security Refers to institutuional and personal security measures designed to prevent the loss, theft, misuse or intentional release of pathogens and toxins

32. Biosafety and Biosecurity Biosafety and Biosecurity Appropriate policies and measures applied to minimize relevant biological risks (Minimize the risks don’t waste time debating the definitions)

33. Risk assessment and Policy For ex. Polio

34. Biological threats to: Agriculture, fisheries & forestsAgriculture, fisheries & forests Natural resourcesNatural resources International and domestic tradeInternational and domestic trade Tourism & LifestyleTourism & Lifestyle Economy & infrastructureEconomy & infrastructure Public health & safetyPublic health & safety Agriculture, fisheries & forestsAgriculture, fisheries & forests Natural resourcesNatural resources International and domestic tradeInternational and domestic trade Tourism & LifestyleTourism & Lifestyle Economy & infrastructureEconomy & infrastructure Public health & safetyPublic health & safety

35. Avian Infleuenza

36. Bio-security program Comprehensive programComprehensive program Cover the whole field of activitiesCover the whole field of activities An updated inventoryAn updated inventory Level of accessLevel of access Description of useDescription of use Documentation of any transfersDocumentation of any transfers

37. Risk management approach A modern risk management framework (SA/SNZ 1999) Establish the context Identify risks Analyse risks Treat risks Monitor and Review Evaluate risks International risk management methods can be applied to all areas of economies, community and environment Communicate and Consult

38. Training Identifying the rationale of these precautions