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Stem cells: disease models and therapeutics Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL.

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Presentation on theme: "Stem cells: disease models and therapeutics Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL."— Presentation transcript:

1 Stem cells: disease models and therapeutics Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL.

2 Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL. Opportunities Therapy Mechanisms of Repair Cellular Models Disease Mechanisms

3 Stroke Human Neural stem cells

4 iPS cells from human keratinocytes SHANK3 domain structure Deleted region: exons Oct4 biopsy keratinocytes piggybac iPS cells Neural progenitors Neurons Cellular Assays

5 EC The Charles Wolfson Charitable Trust Aaron Jeffries Dafe Uwanogho Graham Cocks Zahra Hassani Leo Perfect Sandrine Thuret Nick Bray Carmine Pariante Jon Mill Leo Schzlkwyk Eva Syková Pavla Jendelová Govindan Dayanithi Mike Modo Ellen Bible Nataliya Gorenkova


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