1. PSYC 2314 Lifespan Development Chapter 3 Heredity and Environment

2. Development Begins Conception occurs when the male gamete (sperm) penetrates the membrane of the female gamete (the ovum); the gametes then fuse, and their genetic material combines, to form the one-celled zygote. Within hours, the zygote initiates the human development through the processes of duplication and division. Soon after, differentiation begins. Each body cell created from these processes carries an exact copy of the zygote’s genetic instructions.

3. Development Begins Instructions on each gene that specify the form, location, and function of each body cell are “written” in a chemical code made up of four bases: –Adenine –Guanine –Cytosine –Thymine

4. Development Begins The 23 rd pair of chromosomes, which determines sex, is designated XY in the male and XX in the female. The critical factor in the determination of the zygote’s sex is which sperm reaches the ovum first, a Y sperm, creating a boy, or an X sperm, creating a girl.

5. Development Begins Genes accomplish two goals that are essential to our survival: –Ensure genetic continuity across the species –Ensure genetic diversity within it

6. Development Begins Age-related changes in the sex ratio –Worldwide, slightly more males than females are born each year. –Because males have a slightly higher rate of childhood death, a balance occurs at about 25. –After age 50, the sex ratio favors women.

7. Development Begins Monozygotic Twins –A single zygote splits into two separate identical cells that develop into genetically identical, who have the potential for developing the same physical appearance and psychological characteristics and the same vulnerability to specific diseases.

8. Development Begins Dizygotic Twins –Begin life as two separate zygotes and share no more genes than any other siblings.

9. Genotype to Phenotype Polygenetic: affected by many genes Multifactorial: influenced by many factors, including environmental Genotype: the sum total of all the genes a person inherits Phenotype: the sum total of all the genes that are actually expressed

10. Genotype to Phenotype Additive gene: when genes interact additively, the phenotype reflects the contributions of all the genes that are involved. Dominant gene: the stronger of an interacting pair of genes. Recessive gene: the weaker of an interacting pair of genes.

11. Genotype to Phenotype X-linked Genes: genes that are on the X chromosome. –If an X-linked gene is recessive—as are the genes for most forms of color-blindness, many allergies, several diseases, and some learning disabilities—the fact that it is on the X chromosome is critical.

12. Genotype to Phenotype Genetic Imprinting –Certain genes tend to be expressed differently when they are inherited from the mother than when they are inherited from the father. –Some of the genes that influence height, insulin production, and several forms of mental retardation affect a child in different ways— even in opposite ways—depending on which parent they came from.

13. Genotype to Phenotype Effects of genes and environment on development –Research has revealed that most behavioral traits are affected by the interaction of large number of genes with environmental factors. –Genes are part of a person’s basic foundation, affecting many aspects of life while determining none. –Even traits that show a strong genetic influence are also affected by environment.

14. Environmental Influences on Emotional Impairment The following psychological traits have strong genetic influences, but they are also affected by the social atmosphere: –Shyness (inhibition) –Intelligence –Emotionality –Activity level –Aggression

15. Environmental Influences of Mental Disorders Both genes and environment are influential in determining psychopathologies: –Depression –Phobias –Antisocial behavior –Schizophrenia –Alcoholism

16. Inherited Abnormalities Major Methods of Prenatal Diagnosis: –Pre-implantation Testing –Alphafetoprotein Assay –Ultrasound

17. Inherited Abnormalities Prenatal Testing: –Fetoscopy –Amniocentesis –Chorionic Villi Sampling

18. Chromosomal Miscount Down Syndrome (Trisomy-21) –Individual has 3 chromosomes at site 21 –Specific facial characteristics: round face, thick tongue, unusual eyes. –Also, heart abnormalities, hearing problems, muscle weakness, mental retardation, and short stature

19. Chromosomal Miscount Abnormalities at the 23 rd location –At the 23 rd pair, either missing a X chromosome or has two or more other sex chromosomes in addition to the first X. –Impair cognitive and psychosocial development and sexual maturation

20. Chromosomal Discount The Fragile X –A disorder in which part of the X chromosome is attached to the rest of it by a very slim string of molecules. –Mental deficiency –Inadequate social skills and extreme shyness

21. Harmful Genes Huntington’s Chorea –A central nervous system disease caused by a gene that remains inactive until adulthood, by which time a person could have had many children. Tourette Syndrome –Exhibit recurrent uncontrollable tics and explosive outbursts of verbal obscenities (30%). An occasional twitch and a postponal impulse to speak inappropriately (70%).

22. Genetic Counseling Situations in which couples should seek genetic testing and counseling: –Individuals who have a parent, sibling, or child with serious genetic condition. –Couples who have a history of early spontaneous abortions, stillbirths, or infertility.

23. Genetic Counseling Situations in which couples should seek genetic testing and counseling: –Couples who are from the same ethnic group or subgroup—especially if the group is a small one or most particularly if the couple are close relatives. –Women over age 34.