1. TUPDD0104: Will an innovative, unsupervised HIV self-testing strategy work in health care professionals? A feasibility study from South Africa Primary o Feasibility –defined by completion rate of strategy, i.e. conduct, interpretation and linkages. Secondary o HIV Seropositivity & accuracy o Disagreement between self rated risk and calculated risk o Qualitative: Patient experience, concerns about self testing P OPULATION I NTERVENTION S ETTING Groote Schuur Hospital Un-supervised self-testing strategy with internet- based application vs. paper based application and linked mobile phone-based counseling. Cape Town, South Africa 251 Healthcare professionals O BJECTIVE

2. Results Quantitative Qualitative outcomes analyzed from open responses *Of 251, 78% female, 63% with no history of recent HIV testing. *Of 251, 125 internet & 126 paper *249 (99.2%) completed self testing; *Completion rate sero-positives: 100% [95% CI (66%, 100%)]. *Completion rate in sero-negatives: 44·6% [95% CI (38%, 51%)] *Seropositivity: 3·6% [95% CI: 1·8, 6·9] *Of 9 positives (2 faint positive +1 m); * Sn: 66.7% ;Sp: 100% ;PPV: 100% NPV: 98.8% *Disagreement of perceived risk vs. calculated risk: 55% (138); *91% rated self test exp- good. “I think this is the best method, as most people don’t like queuing in clinics for HIV testing. Now this is very easy and fast way of knowing HIV status.” *** “ Risk staging opened my eyes-I thought I thought I was very safe but now I know I am at high risk and I don’t think the questions are too personal.” *** “It’s very good because you test anytime in the privacy of your own home and it’s easy.” *** I wish you can take it to our communities as well because there are people who would love to use it as there are no privacies anymore in our clinics.”

3. Un-supervised self-testing strategy with internet-based application vs. paper based application and mobile phone-based counseling I NTERVENTIONS I NTERNET - BASED A PPLICATION P APER - BASED A PPLICATION HIV S MARTPHONE A PPLICATION N ITIKA P ANT P AI, MD, MPH, PhD McGill University Canada Nitika.pai@mcgill.ca Dr Keertan Dheda, MD PhD Dr Lawrence Joseph, PhD