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The NICE experience Christine Baldwin Division of Medicine, Imperial College London & The Royal Marsden Hospitals, London PEN Group Annual Conference,

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Presentation on theme: "The NICE experience Christine Baldwin Division of Medicine, Imperial College London & The Royal Marsden Hospitals, London PEN Group Annual Conference,"— Presentation transcript:

1 The NICE experience Christine Baldwin Division of Medicine, Imperial College London & The Royal Marsden Hospitals, London PEN Group Annual Conference, London, August 2006

2 Structure Process Type of evidence Implications for dietitians

3 The need for this guideline Malnutrition is common Nutritional provision in hospital and community may be inadequate Provision of nutritional support requires complex decisions Wide variation in nutritional care standards

4 Topic nomination are still capable of deriving some of their nutritional requirements by conventional feeding and/or have difficulty swallowing including the use of nutritional supplements and enteral and parenteral feeding methods DoH and Welsh Assembly to develop a guideline on appropriate methods of feeding patients who:

5 The process (1) Proposal National Collaborating Centre for Acute Care (NCCAC) Scope stakeholders

6 The process (2) Guideline Development Group: Clinicians GP Dietitians (2) Speech & Language Therapist Nurses Patient Groups pharmacists

7 The process (3) Development of clinical questions

8 Clinical questions P atients –Malnourished patients I ntervention –More food or nutritional supplement C omparison –No intervention O utcomes –mortality

9 Process (4) Literature search Review of papers Extraction of data on identified outcomes

10 Process (5) Development of guidelines from evidence base 1st consultation 2nd consultation Final guideline produced Stakeholder comments

11 The guideline Quick reference guide (a summary) NICE guideline (all of the recommendations) Full guideline (all of the evidence and rationale) Information for the public (a plain English version)

12 Changing clinical practice Department of Health has asked NHS organisations to work towards implementing the guidelines Compliance will be monitored by the Healthcare Commission NICE guidelines are based on the best available evidence

13 Aims of the guideline Authoritative evidence-based guidelines on nutritional support : –Who? –When? –What? –How ? excluding children and immunonutrition

14 Valid evidence Systematic review of multiple randomised controlled trials (RCTs) Large RCTs Non-randomised, case-control studies Non-experimental studies from more than one centre Opinions based on clinical evidence

15 Problems of evidence (1) Study design Which studies are included Heterogeneity Study quality Definition of malnutrition Interventions

16 Problems of evidence (2) Wanted: volunteers for randomized, placebo controlled trial

17 No evidence available NICE found no RCTs with the introduction of screening as the intervention that then looked at either change in process or clinical measures as outcomes.

18 NICE argument: Even if evidence proves that nutrition support is effective, it does not necessarily follow that screening for malnourishment is of benefit

19 Potential Solutions Potential benefits of nutrition support may be better addressed by non-RCT techniques (but NICE lack the resources) NICE recognized our problems and allowed some Guidance based on first principles Formal Consensus Techniques (but lack of time)

20 Nutritional screening Inpatients Outpatients Residents of care homes Attendees of GP surgeries should all be screened for risk of malnutrition (D (GPP))

21 Grading of evidence A meta-analysis or good quality RCT B extrapolated evidence from good quality RCTs or meta-analysis of cohort studies C D D (GPP) good practice point

22 Recommendations 77 recommendations 10 priorities for implementation 5 research recommendations Grade A = 8 Grade B = 9 Grade D (GPP) = 60

23 Key priorities for implementation 10 recommendations: –Screening (3) –Identification (2) –Nutritional support (1) –Education (4)

24 Nutritional screening Inpatients Outpatients Residents of care homes Attendees of GP surgeries should all be screened for risk of malnutrition (D (GPP))

25 Screening Two most important features: linked to effective treatment pathway leads to beneficial outcome

26 Numbers of: hospital inpatients (n=11,157) hospital outpatients (n=10,823) community Implications (1)

27 Implications (2) Who will carry out screening? Need adequate numbers of dietitians Who will raise awareness? referrals available to see patients provide training

28 Research recommendation: Would a screening programme for all patients impact on clinical outcomes (LOS, QOL, complications), compared with no screening? Implications (3)

29 Education Screening for malnutrition and the risk of malnutrition should be carried out by healthcare professionals with appropriate skills and training to enable accurate data collection (D (GPP))

30 Implications (1) Staff training: Clear procedures medical staff nursing staff management

31 Implications (2) Research recommendation: Further research is needed to ascertain whether an educational intervention … for all healthcare professionals … would have an affect on patient care [LOS, QOL, complications], compared to no formal education.

32 Oral nutritional intervention Healthcare professionals should consider oral nutrition support to improve nutritional intake for people who can swallow safely and are malnourished or at risk of malnutrition. (A)

33

34 The debate Nutritional supplements Dietary advice Dietary advice + nutritional supplements vs

35 Implications (1) Can dietitians see all the patients that need intervention? Which intervention? develop policies training to ensure consistency

36 Research recommendation: Benefits to patients at nutritional risk offered sip feeds vs dietary counselling: Implications (2) survival complication rate LOS QOL cost

37 Consider enteral tube feeding (ETF): and use the most appropriate route of access and mode of delivery stop when the patient is established on adequate oral intake from normal food surgical patients may have different needs has a functional and accessible gastrointestinal tract if patient malnourished/at risk of malnutrition despite the use of oral interventions

38 Enteral feeding Healthcare professionals should consider enteral tube feeding in people who are malnourished or at risk of malnutrition, respectively, and have: (D (GPP)) inadequate or unsafe oral intake, and a functional, accessible gastrointestinal tract

39 Elective enteral feeding No evidence of clinical benefits Enteral tube feeding should not be given to people unless they are malnourished or at risk of malnutrition and have; inadequate or unsafe oral intake and a functional, accessible gastrointestinal tract, or they are taking part in a clinical trial. (A)

40 Surgical patients: early post-op ETF ETF vs nil by mouth General surgical patients should not have [ETF] within 48 hours post-surgery... (A) do not23 RCTs: combined results do not support the use of early ETF

41 Are they NICE guidelines? Not perfect BUT they do raise the profile of nutritional care and oblige organizations to take it seriously.

42 Challenge and opportunity for dietitians Summary

43 Acknowledgements Joanna Prickett Dietitian, All members of the Guideline Development Group North Bristol NHS Trust


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