1. Cryptogenic Stroke Initiative

2. ~ 800,000 new or recurrent strokes yearly 1 87% ischemic; 13% hemorrhagic 1 690,000 ischemic strokes every year in the US 2 Approximately 200,000 cryptogenic strokes (CS) annually 2 Diagnosis and management of cryptogenic stroke is unclear by many health professionals Cross-collaboration by HCPs along the CS treatment continuum is limited Breadth of monitoring clinical research on CS is limited 1. Mozzafarian D et al. 2015;131:e29-e322 2. American Heart Association 87% ischemic strokes of 795,000 30 % Cryptogenic Stroke Issue of Cryptogenic Stroke

3. Aligning to the AHA/ASA 2020 Impact Goal of reducing cardiovascular disease and stroke mortality by 20%: The American Stroke Association and Medtronic are elevating the issue of cryptogenic stroke because better diagnosing and managing patients will save lives from our nation’s No. 5 killer and a leading cause of serious, long-term disability. Reducing the Burden of Cryptogenic Stroke

4. The Cryptogenic Stroke Initiative During the two years of the Initiative, it will: 1.Track and monitor trends in cryptogenic stroke care through our GWTG-Stroke database and tracking studies 2.Launch a Public Awareness Campaign to educate physicians and stroke patients on best stroke care practices, including local trainings at Stroke Bootcamps 3.Work with thought leaders to drive improved management of cryptogenic stroke in their practices 4.Publish outcomes

5. What Can You Do 1.Engage a dialogue with your staff at your facility around how is it can best manage cryptogenic stroke patients 2.Work with thought leaders in your community to drive improved management of cryptogenic stroke in their practices 3.Consider engaging local media around your leadership in this unknown topic 4.Review current guidelines in management of cryptogenic stroke, found at StrokeAssociation.org/CS 5.Learn more about potential causes of CSpotential causes of CS 6.Seek additional resources at StrokeAssociation.org/CS

6. Resources for You Patient/Caregiver Resources: 1.Cryptogenic Stroke Patient Guide 2.Print Infographic and Animated Infographic 3.Interactive Slide Show Healthcare Professional Resources: 1.Healthcare Professional 2.Pocket Card Algorithm 3.Waiting Room Poster 5.Cryptogenic Stroke Education Deck

7. For More Information StrokeAssociation.org/CS