We think you have liked this presentation. If you wish to download it, please recommend it to your friends in any social system. Share buttons are a little bit lower. Thank you!
Presentation is loading. Please wait.
Published bySebastian McMahon
Modified over 3 years ago
Parenteral Drug Administration Department of Anaesthesia University of Glasgow
Parenteral Route in Dentistry General Dental CouncilGeneral Dental Council –Intravenous sedation drugs –Emergency drugs
Drug Administration Absorbtion Plasma water Metabolism Excretion Site of ActionTissue oral intramuscular subcutanous topicalintravenous
Parenteral Injection Sites subcutanously intramuscularly intravenously
Subcutaneous Route Absorption depending on blood flowAbsorption depending on blood flow –Constant & slow absorption –Prolonged effect Drugs –Insulin –Heparin
Subcutaneous Injection Sites Abdominal wallAbdominal wall ThighThigh Deltoid areaDeltoid area
Intramuscular Route Absorption depending on blood flowAbsorption depending on blood flow –Rapid onset & shorter duration –Shock DrugsDrugs –Glucagon –Adrenaline
Intramuscular Injection Sites
Intramuscular Route LimitationsLimitations –Neurovascular damage –Bleeding (eg anticoagulant therapy) –Pain –Infection –Delayed absorption in shock –Interpretation of diagnostic tests
Intravenous Route Rapid immediate onsetRapid immediate onset Permits titrationPermits titration Administer slowlyAdminister slowly DrugsDrugs –Midazolam
Intravenous Injection Sites PeripheralPeripheral CentralCentral
Intravenous LimitationsLimitations –May be more difficult to obtain –Increased risk of adverse effects –Requires intravenous access –Infection –Pain
Anaphylaxis DefinitionDefinition –Immunologically mediated reaction to antigen causing systemic symptoms Potentially life threateningPotentially life threatening Frequent AntigensFrequent Antigens –Antibiotics –Latex –Anaesthetic agents –Colloid fluids
Anaphylaxis DiagnosisDiagnosis –Collapse –Difficulty breathing –Wheeze –Angio-oedema –Urticaria
Management Anaphylaxis PreventionPrevention –Avoid unnecessary drugs particularly iv –Take drug history Adequate staff training and facilitiesAdequate staff training and facilities
Immediate Management 1 Remove trigger agent –Stop injection or infusion of drug –Remove triggering materials Remember latex allergy Chlorhexidine –Summon assistance
Immediate Management 2 Basic life supportBasic life support –Check airway, breathing, circulation –Oxygen Give adrenaline (0.5-1mg im)Give adrenaline (0.5-1mg im) Elevate legsElevate legs (Give intravenous fluids)(Give intravenous fluids)
Subsequent Management AntihistaminesAntihistamines –Chlorpheniramine iv SteroidsSteroids –Hydrocortisone iv Intensive care unitIntensive care unit Immunological TestingImmunological Testing
Summary Parenteral drug administrationParenteral drug administration –Sites –Drug availability –Limitations AnaphylaxisAnaphylaxis
Parenteral products are dosage forms, which are delivered to the patient by a injection or implantation through the skin or other-external layers such.
Anaesthetic Emergencies Acute Anaphylaxis Dr T E Allan Palmer FRCA FANZCA MD
Pharmacology I BMS 242 Lecture I (Continued) Introduction; Scope of Pharmacology Routes of Drug Administration Dr. Aya M. Serry 2015/2016.
Complications of IV drug Therapy March Site of administration Benefits?Complications?
Pharmaceutics I صيدلانيات 1 Unit 2 Route of Drug Administration
DRUG INTERACTIONS. –Adverse drug effects –Hypersensitivity –Anaphylactic reactions.
Indications: Where IV administration is not available. Drugs with specific actions on muscles. A longer half life is needed eg. Morphine for anaesthesia.
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 35 Intravenous Medications.
Anaphylaxis SHO presentation Tom Francis ICU Registrar.
Fundamental Nursing Chapter 35 Intravenous Medications
Midazolam Use in the Emergency Department
Anaphylaxis. Severe Anaphylactic Reactions Manifestation Respiratory difficulty Signs of shock/hypotension Involvement of skin/mucosal tissue GI symptoms.
Dr. Suzan Hassan. Many studies have shown that medical emergencies do occur in the dental practice so that we need to have appropriate skill and equipment.
Severe Allergic Reaction (Anaphylactic Shock) 过敏性休克 Fang Hong 方 红 1st Affiliated Hospital, Zhejiang University.
Allergies and Anaphylaxis. Sections Pathophysiology Assessment Findings in Anaphylaxis Management of Anaphylaxis Assessment Findings in Allergic.
Management of allergy reaction
Dr. Shahzadi Tayyaba Hashmi. MEDICAL EMERGENCIES THAT CAN OCCUR IN THE DENTAL SURGERY Vasovagal attack (faint/syncope) Hyperventilation (panic attack)
Acute Chemotherapy related reactions
© 2017 SlidePlayer.com Inc. All rights reserved.