1. Abstract ID 1196 CT volumetry of adrenal glands in normal subjects

2. Introduction Wide varieties of the adrenal diseases that lead to morphologic changes in adrenal glands. Adrenal gland is variable in shape and size Adrenal thickness- Considered as a useful parameter Measuring volume will be more appropriate than the size of the gland With multidetector spiral computed tomography, the determination of adrenal volume has become possible in recent years.

3. To date, only limited studies available. – Based on western and chinese population However no studies are available for CT volumetry of adrenal gland volume in indian populations.

4. Aim and objective To calculate volumetry of adrenal glands in patients reported for CT abdomen without any clinical evidence of diseases related to adrenals

5. Materials and method PROTOCOL : Non contrast CT KUB or Abdomen, helical, 2mm slice thickness in 16 slice multidetector CT. INCLUSION CRITERIA: Patients of both sexes and different age groups(20-40 yrs) reporting for CT KUB or Abdomen EXCLUSION CRITERIA: Patients with clinical /biochemical suspicion of adrenal disease. Patients having diseases in which adrenal involvement suspected. Patients with known malignancy.

6. Study Design Study population :(100) (50males and 50 female ) Clinical data collected and pt underwent NCCT Volume calculated in axial section by summing areas of all relavant sections X 2

7. Calculation of adrenal gland volume on CT

9. Results

10. Age distribution

11. Adrenal gland volumes in cc- all cases RightLeftTotal Mean3.283.366.633 SD0.426570.4316590.715994

12. Shapes of the adrenal gland Adrenal gland shapeRightLeft Linear 904 V shaped 378 Y shaped 016 Curvilinear 71 Triangular 01

13. MaleFemaleComparison (T test) Adrenal volumes in cc MeanSDMeanSDp value Right3.300.4633.270.3900.764 Left3.450.4183.260.4260.026 Total6.750.7816.520.6310.137

14. Discussion No significant difference in the mean right and total adrenal gland volumes between males and females (p values 0.76 and 0.137 respectively for right and total gland volumes). However there is a statistically significant difference in the volumes of left adrenal glands (p value= 0.026), being larger in females. The results are comparable with studies done in the western population(Mean volume 3.62cc for Right and 3.73cc for Left)(4,5). However as compared with chinese studies, Significantly smaller volumes of indian population could be representative of our genetic make up.(Mean volume 4.23 and 4.26)(6).

15. References 1.Vincent JM, Morrison ID, Armstrong P, Reznek RH. Clin Radiol. The size of normal adrenal glands on computed tomograp1994 Jul;49(7):453-5 2.Anand MK, Anand C, Choudhry R, Sabharwal A. Morphology of human suprarenal glands: a parameter for comparison. Surg Radiol Anat. 1998;20(5):345-9. 3.Jung B, Nougaret S, Chanques G, et al. The absence of adrenal gland enlargement during septic shock predicts mortality: a computed tomography study of 239 patients. Anesthesiology 2011; 115:334-43. 4.Rubin RT, Phillips JJ. Adrenal gland volume determination by computed tomography and magnetic resonance imaging in normal subjects. Invest Radiol 1991; 26:465-9. 5.Ma G, Liu SW, Zhao ZM, et al. Sectional anatomy of the adrenal gland in the coronal plane. Surg Radiol Anat 2008; 30:271-80 6.Wang X, Jin ZY, Xue HD, Liu W, Sun H, Chen Y, Xu K. Evaluation of Normal Adrenal Gland Volume by 64-slice CT. Chin Med Sci J.2013 Jan;27(4):220-4

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