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Cells and Their Environment Chapter 4. 4.1 Passive Transport Part 1: Diffusion Remember: Living things need to maintain homeostasis (responds to external.

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Presentation on theme: "Cells and Their Environment Chapter 4. 4.1 Passive Transport Part 1: Diffusion Remember: Living things need to maintain homeostasis (responds to external."— Presentation transcript:

1 Cells and Their Environment Chapter 4

2 4.1 Passive Transport Part 1: Diffusion Remember: Living things need to maintain homeostasis (responds to external conditions to maintain a stable internal condition) One way to do this is controlling the movement of things in and out of a cell

3 Passive Transport Requires no energy Requires no energy Diffusion is the movement of a substance from an area of high concentration to an area of low concentration by random movement Diffusion is the movement of a substance from an area of high concentration to an area of low concentration by random movement A difference in concentration of a substance across a space is a concentration gradient A difference in concentration of a substance across a space is a concentration gradient

4 Equilibrium is where the concentration is equal Equilibrium is where the concentration is equal Since the interior of a cell is different from its external environment substances move back and forth through the cell membrane Since the interior of a cell is different from its external environment substances move back and forth through the cell membrane The membranes lipid interior repels ions and polar molecules. WHY!! The membranes lipid interior repels ions and polar molecules. WHY!!

5 The diffusion of small or nonpolar particles across the cell membrane is the simplest form of passive transport The diffusion of small or nonpolar particles across the cell membrane is the simplest form of passive transport

6 Part 2: Osmosis The diffusion of water through a selectively permeable membrane The diffusion of water through a selectively permeable membrane Water moves down the concentration gradient Water moves down the concentration gradient When something is dissolved in water its molecules are attracted to the water molecules When something is dissolved in water its molecules are attracted to the water molecules This causes a difference between free water and non-free water This causes a difference between free water and non-free water This causes the concentration gradient This causes the concentration gradient

7 Hypertonic Solution Hypertonic Solution Fluid outside has higher concentration of dissolved substances than fluid inside the cell Fluid outside has higher concentration of dissolved substances than fluid inside the cell Causes water to diffuse out of cell Causes water to diffuse out of cell Cell shrinks Cell shrinks

8 Hypotonic Solution Hypotonic Solution Fluid inside has higher concentration of dissolved substances than fluid outside cell Fluid inside has higher concentration of dissolved substances than fluid outside cell Causes water to diffuse into cell Causes water to diffuse into cell Cell swells Cell swells

9 Isotonic Solution Isotonic Solution Fluid inside has same concentration of dissolved substances as fluid outside cell Fluid inside has same concentration of dissolved substances as fluid outside cell Causes no net water movement Causes no net water movement Water moves in and out at equal rates Water moves in and out at equal rates Equilibrium – no change in size Equilibrium – no change in size

10 How does this affect you?

11 Cells have ways of dealing with swelling or shrinking Cells have ways of dealing with swelling or shrinking Cell walls keep cells from expanding too much Cell walls keep cells from expanding too much Some unicellular eukaryotes have contractile vacuoles to collect excess water and force it out Some unicellular eukaryotes have contractile vacuoles to collect excess water and force it out Animal cells remove dissolved particles to stop osmosis Animal cells remove dissolved particles to stop osmosis

12 Part 3: Crossing the Cell Membrane Transport Proteins called channels help polar substances cross cell membrane Transport Proteins called channels help polar substances cross cell membrane Each only allows 1 kind of substance through Each only allows 1 kind of substance through

13 Diffusion through ion channels Diffusion through ion channels Many ions are important for cell functions Many ions are important for cell functions Important in heartbeat and nerve cellsImportant in heartbeat and nerve cells Ion channels are transport proteins with a polar pore so ions can pass through membrane Ion channels are transport proteins with a polar pore so ions can pass through membrane Ions pass without touching nonpolar lipid tails Ions pass without touching nonpolar lipid tails

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15 Ion channel gates allow some to open and close in response with stimuli Ion channel gates allow some to open and close in response with stimuli Stretching of cell membrane Stretching of cell membrane Change in electrical charge Change in electrical charge Binding of specific molecules to channel Binding of specific molecules to channel No use of energy so Passive Transport No use of energy so Passive Transport

16 Electrical Charge and Ion Transport Electrical Charge and Ion Transport Positive or negative charge affects movement of charged particle across membrane Positive or negative charge affects movement of charged particle across membrane Inside of cells are negatively charged compared to outside Inside of cells are negatively charged compared to outside This causes positively charged particles to want to move in and the negative ones to want to move out (trying to reach equilibrium) This causes positively charged particles to want to move in and the negative ones to want to move out (trying to reach equilibrium)

17 Facilitated Diffusion Facilitated Diffusion Carrier Proteins (a kind of transport protein) bind to a specific substance and carry it across membrane and release it Carrier Proteins (a kind of transport protein) bind to a specific substance and carry it across membrane and release it Still moving down concentration gradient Still moving down concentration gradient Carrier protein attaches to substance on one sideCarrier protein attaches to substance on one side Shape of protein changes bringing substance throughShape of protein changes bringing substance through Substance protected from lipids and is released and protein goes back to original shapeSubstance protected from lipids and is released and protein goes back to original shape Passive Transport Passive Transport

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19 4.2 Active Transport Part 1: Movement Against a Concentration Gradient When concentration is higher inside than outside, cells must move things against gradient from low to high When concentration is higher inside than outside, cells must move things against gradient from low to high Called Active Transport Called Active Transport Requires energy, usually ATP Requires energy, usually ATP

20 Sometimes uses carrier proteins Sometimes uses carrier proteins Since moving against gradient, called membrane pumps Since moving against gradient, called membrane pumps

21 Sodium-Potassium Pump Sodium-Potassium Pump 3 sodium ions, Na+, out and two potassium ions, K+, in 3 sodium ions, Na+, out and two potassium ions, K+, in Active transport of both Active transport of both Sodium higher outside and potassium higher insideSodium higher outside and potassium higher inside Energy supplied by ATP Energy supplied by ATP

22 How Does ATP Work? ATP is Adenosine TriPhosphate ATP is Adenosine TriPhosphate 3 phosphate groups attached to the sugar Ribose and the base, Adenine 3 phosphate groups attached to the sugar Ribose and the base, Adenine

23 Phosphates are negative so they repel each other and are unstable Phosphates are negative so they repel each other and are unstable A little energy in causes one phosphate to break off and more energy is given off A little energy in causes one phosphate to break off and more energy is given off This causes ATP to become ADP, Adenosine DiPhosphate This causes ATP to become ADP, Adenosine DiPhosphate Cell uses energy given off from this reaction Cell uses energy given off from this reaction

24 Sodium-Potassium Pump 3 Na+ inside bind to pump and a phosphate group leaves ATP and binds to pump 3 Na+ inside bind to pump and a phosphate group leaves ATP and binds to pump Pump changes shape and 3 Na+ are released outside Pump changes shape and 3 Na+ are released outside 2 K+ bind to pump and are transported across 2 K+ bind to pump and are transported across 2 K+ and P from ATP is released inside cell 2 K+ and P from ATP is released inside cell

25 Pump prevents Na+ from building up in cell since it constantly flows in due to diffusion Pump prevents Na+ from building up in cell since it constantly flows in due to diffusion This build up would cause water to flow in due to osmosis, causing the cell to swell or burst This build up would cause water to flow in due to osmosis, causing the cell to swell or burst Allows K+ to be brought in Allows K+ to be brought in Many cells use Na+ pump to bring in things they need Many cells use Na+ pump to bring in things they need

26 Part 2: Movement in Vesicles Some things are too large to use carrier proteins Some things are too large to use carrier proteins Vesicles used instead Vesicles used instead

27 Endocytosis when moved in Endocytosis when moved in Cell membrane forms a pouch around a substance, closes up and pinches off forming vesicle Cell membrane forms a pouch around a substance, closes up and pinches off forming vesicle Vesicle may fuse with lysosomes or other organelles Vesicle may fuse with lysosomes or other organelles

28 Exocytosis when moved out Exocytosis when moved out Vesicles inside fuse with membrane and release contents Vesicles inside fuse with membrane and release contents Used for proteins modified by Golgi apparatus Used for proteins modified by Golgi apparatus Nerve cells and gland cells release proteins Nerve cells and gland cells release proteins


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