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Any change in the DNA base sequence is called a mutationGenetic Mutations Any change in the DNA base sequence is called a mutation
Why is the Tiger White DNA mRNAproteinMutations are changes in the genetic code Some changes are lethal, and some don’t matter at all. (This tiger is white because of a genetic mutation)
Mutations in gamete cells mutation passed on to offspringMutations in body cells damage to a gene = cell malfunction. New cells will also have malfunction
How do Mutations happen?Mutations: good, bad or neutral- most often neutral Spontaneous Nuclear radiation Ultraviolet light- sunlight Chemicals Mutagen- causes mutations
Decode this sequence mRNA ACU– GGA – CCA -- UUC Protein ____ _____ ____ ____ threonine glycine proline phenylalanine Now change just the last C to a G What do you get? leucine
A change of one base is called a point mutationmRNA ACU– GGA – CCA -- UUC threonine glycine proline phenylalanine Change the last C to a U- what happens? Sometimes point mutations don’t matter
Insertions and Deletions are Frameshift mutationsmRNA ACU– GGA – CCA -- UUC Take out the first C AUG-- GAC– CAU– UC Meth ASP Hist ??? Called Frame shift mutations
Mutations Point mutations (substitutions)- may or may not be a big deal Frame shift mutations (insertions or deletions)- always a big deal
Example of a point mutationSickle cell anemia One base change- one amino acid substitution Hemoglobin does not function normally
TTGACATACCCGTAAT What would the complementary strand of this DNA molecule read? AACTGTATGGGCATTA.
MUTATIONS. Mutations are heritable changes in genetic information Only mutation in the GAMETES can be passed on from generation to generation There can.
Ch Mutations Section Objectives:
Chromosomes and Genes Each chromosome has hundreds or thousands of genes. Each gene codes for a particular protein.
DNA, Genes, and Proteins Characteristics are based on the same genetic code stored in DNA.
Mutations. What Are Mutations? Changes in the nucleotide sequence of DNA May occur in somatic cells (aren’t passed to offspring) May occur in gametes.
Chapter 11.6 Mutations. Definition- Mutation- a change in the DNA nucleotide sequence Mutation- a change in the DNA nucleotide sequence Types of mutations:
During replication (in DNA), an error may be made that causes changes in the mRNA and proteins made from that part of the DNA These errors or changes.
DNA Mutations What is a mutation? 1) Change in the DNA of a gene. 2) When a cell puts its genetic code into action it is making precisely the proteins.
Section 13.3/4: “Mutations & Gene Expression” Text Pages
Decoding DNA Worksheet
Genetic Changes: Mutations Chapter I. MUTATION ANY change in an organisms DNA sequence Causes Errors in replication Transcription Cell.
Wednesday, January 16 th What is a mutation? Reminders: DNA Test Friday.
1.Most genetic disorders result from a mutation in one gene. a.Mutation: a change in an organism’s genetic material (DNA) 2.A mutated gene produces a.
Protein synthesis continued. Transcription is step 1 DNA mRNA Nucleus RNA polymerase.
Mutations. Mutation effects Reproductive Cells -mutation in DNA sequence of an egg or sperm cell -mutation is passed on to offspring - possible effects.
DNA Mutations. Remember that during DNA replication, the DNA makes an exact copy of itself before it divides. DNA replication is not always accurate.
4.12 DNA and Mutations. Quick DNA Review Base pairing Base pairing.
Biology 12. WHAT ARE MUTATIONS? Changes in the nucleotide sequence of DNA May occur in somatic cells (aren’t passed to offspring) May occur in.
12.4 Mutations Copyright Pearson Prentice Hall.. What Are Mutations? Changes in the nucleotide sequence of DNA (genetic material) May occur in somatic.
Mutations. What comes to mind???? Mutants.
1 NOTES: MUTATIONS 2 MUTATIONS: MUTATIONS = changes in the DNA sequence that affect genetic information.
the Genetic Code Shown as mRNA 5′ → 3′ 64 codons Redundant
MS-LS 3-1. I will explain how mutations can effect organisms in positive, negative, and neutral ways.
What is a mutation? A mutation is any change in genetic material. There are many ways for mutations to occur. Common point mutations are...
Fantasy Mutations Reality. Mutations: a permanent and heritable change in the nucleotide sequence of a gene. Are caused by mutagens (x-rays and UV light)
Gene Mutations Sickle Shaped Red Blood Cells. What is a gene mutation? Mutations are changes in genetic material – changes in DNA code – thus a change.
Mutations Chapter Types of Mutations The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet.
Figure 17.0 Ribosome. DNA and protein DNA codes for your traits So you are different from other people because your DNA is different DNA works by creating.
Mutations in DNA changes in the DNA sequence that can be inherited can have negative effects (a faulty gene for a trans- membrane protein leads to cystic.
GENETIC MUTATIONS What is this picture depicting?.
Mutations Chapter 12-4.
DNA (Gene) Mutations. What is a gene mutation? Often times, parts of DNA will have a base (or more) missing, added, or incorrect.
BIOLOGY HONORS MUTATIONS. WHAT IS A MUTATION? A change in DNA Can cause changes in organism Happen randomly Can be beneficial, neutral, or harmful For.
Mutations Dr. Evil: I have one simple request. And that is to have sharks with frickin' laser beams attached to their frickin’ heads!... What do we have?
13-3 Mutations Can be good, bad or nothing!!. What is a mutation? The word is Latin for “to change”. There are 2 types: – 1) Single gene changes – 2)
Ch Mutations Section Objectives: Categorize the different kinds of mutations that can occur in DNA. Compare the effects of different kinds of mutations.
Genetic Mutations Increasing Genetic Diversity May 4, 2010.
Mutations (12.4) State Standard
Mutations. Mutation Permanent changes or errors in a DNA sequence Copied during DNA replication Therefore heritable OR may occur during transcription.
What ’ s the Purpose of All This DNA Stuff? *Sequence of nitrogen bases along the DNA strand (genes) code for an amino acid sequence (which make up proteins)
DNA, Mutations and Hazardous Waste. Prokaryote Cell.
A change in the nucleotide sequence of DNA Ultimate source of genetic diversity Gene vs. Chromosome.
M UTATIONS. Remember: Before RNA can be transcribed, the two strands of DNA must first __________ between the ______________. Quick ReviewQuick Review.
Mutations in DNA. Mutations A mutation is a change in a DNA sequence. Can happen if – There is a mistake in replication. – Bases change spontaneously.
Genetic Mutations Accelerated Biology. What is a Mutation? A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA.
Lesson Overview 13.3 Mutations.
Mutations. What are mutations? -They are mistakes made in our genetic code, which may or maynot result in the wrong protein being made.
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