1. I. Circulation A. Circulatory systems 1. gastrovascular cavity - very simple - flatworms

2. 2. open circulation - blood pumped through open-ended vessels - “bathes” the tissues - many mollusks and all arthropods

3. 3. closed circulation

4. - arteries (carry blood away from the heart) - veins (carry blood back to the heart)

5. 4. functions a. transport b. regulation - hormones - temperature c. protection - white blood cells - antibodies

6. B. Heart 1. peristaltic pump to:

7. 2. fish (tube-like heart with two adjacent chambers) a. atrium (collects just enough blood to fill ventricle) b. ventricle (thick-walled muscular pump) c. single circuit d. loses force in the gills (slows down)

8. 3. amphibians a. double circulation - pulmonary circuit - systemic circuit - pump blood to muscles at higher force b. three-chambered heart (mixing of blood in ventricle) (won’t damage the lungs) - some transcutaneous gas exchange

9. 4. reptiles a. three-chambered heart b. partial septum in ventricle (less mixing)

10. 4. mammals, birds, crocodilians a. four-chambered heart b. complete separation of the ventricles c. no mixing (much more efficient) d. birds and mammals evolved independently

11. C. Blood 1. plasma a. transport of nutrients/wastes b. proteins - clotting factors - antibodies

12. 2. cells a. red blood cells b. white blood cells c. platelets

13. 3. stem cells

14. II. Respiration A. Gas exchange

15. II. Respiration A. Gas exchange 1. direct diffusion - primitive

16. 2. transcutaneous respiration - most practitioners are small - requires water

17. 3. gills - thin sheets of tissue - contain blood vessels - countercurrent flow

18. 4. tracheal system a. insects b. spiracles - reduces water loss

19. c. tracheoles penetrate the body and provide gas exchange - insects don’t use circulatory system to deliver O 2

20. 5. lungs - have small sacs (alveoli) lined with thin layer of fluid

21. B. Gill apparatus 1. fish “gulps” water 2. water passes over gills, then exits through gill slit 3. countercurrent flow (allows countercurrent exchange) a. water and blood flow in opposite directions b. very efficient method of gas exchange

23. C. Amphibian lung 1. very small without much surface area for gas exchange - not very efficient 2. rely on transcutaneous respiration 3. may lack lungs completely (some salamanders)

24. D. Reptiles 1. more efficient than amphibian - increased surface area for gas exchange 2. most have lower metabolic rate than mammals - less need for high-volume gas exchange

25. E. Mammals 1. many tiny air sacs (alveoli) 2. greatly increased surface area for gas exchange - about 100 m 2 in human lungs 3. air conduction system lined with ciliated cells - mucus elevator

26. F. Birds 1. posterior and anterior air sacs 2. one way flow of air through lungs 3. countercurrent flow - but 90˚, not 180˚ as in fish 4. highest efficiency of land animals