1. Pathophysiology and proposal writing Paul Saunders, John Yan & Mei-Ling Tsai paulrsaunders@gmail.com drosouv@gmail.com mltsai@mail.ncku.edu.tw

2. Objectives Articulate the impact of a specific disease on human life Integrate basic concepts of Physiology, Cell Biology, and Molecular Biology to elaborate the progression of the disease Identify a benefit and limitation in revealing the pathogenesis of the disease Propose a solution to overcome the limitation of understanding the disease

3. Course Design Presentation and Discussion on a specific diseases selected Articulate the impact of a specific disease on human life Integrate basic concepts of Physiology, Cell Biology, and Molecular Biology to elaborate the progression of the disease Guided paper reading and Presentation on how to Identify a benefit and limitation in revealing the pathogenesis of the disease Propose a solution to overcome the limitation of understanding the disease Hand-on practice on writing a proposal based on the skills learned

4. Part I: Presentation and Discussion on a specific diseases selected Identify textbooks and review articles to answer the questions proposed in the discussion of the disease Prepare the outline of the presentation on pathogenesis of the disease Write a summary about the pathogenesis of the disease Discussion on 1.possible impact of a specific disease on human life 2.potential mechanisms of the disease to Integrate basic concepts of Physiology, Cell Biology, and Molecular Biology and elaborate the progression of the disease Guided paper reading and Presentation on how to do Identify a benefit and limitation in revealing the pathogenesis of the disease Propose a solution to overcome the limitation of understanding the disease Hand-on practice on writing a proposal based on the skills learned Course Activities

5. Part II: Guided paper reading and Presentation on how to Identify a benefit and limitation in revealing the pathogenesis of the disease Propose a solution to overcome the limitation of understanding the disease 1.Analyze the paper and find the structure on how to a.Identify a benefit and limitation in revealing the pathogenesis of the disease b.Propose a solution to overcome the limitation of understanding the disease 2.Search a research paper highly related to your study 3.Present the paper and show the outline of the paper Course Activities

6. Part III: Hand-on practice on writing a proposal based on the skills learned Write a proposal outline based on the knowledge learned in Part I and skills exercised in Part II. Complete the proposal for peer edition on the structure and then wording Course Activities

7. Major outcome of the Course Construction of scientific knowledge Integration of scientific knowledge with academic skills Writing/Presenting through Collaborative Process (working with instructors & classmates through reasoning and asking questions in class) Speaking out if here different advice or opinions and asking “why?”

8. Brainstorming

9. HOMEWORK in week 1: 1) collect resource material & READ on your target disease (eg. review article(s); textbook [normal & pathophysiology] and bring references and your outline PPT to next class for further discussion 2) review the powerpoint files on presenting and create a checklist on your presentation, including story development & outlines 3) propose an outline on PPT for the first presentation on pathogenesis of the disease

10. In-class activities in week 2 will include: reviewing the outline for the first presentation and analyzing content for upcoming presentations proposing a summary paragraph Materials to Have (Bring) for Next Class resource material (or summary notes you have made from them (remember normal physiology & pathophysiology – pathogenesis) a PPT for the outline a possible summary paragraph (hard copy and/or electronic copy for all above)