3 Catecholamines stimulate HSL to break down triglycerides to fatty acids and glycerol Fatty acids and glycerol are released into the blood and circulated to other body tissues
4 ATGL Adipose Triglyceride Lipase Enzyme that may be responsible for catalyzing the initial steps of triglyceride hydrolysis.Zimmermann et al. (2004)HSL knock-out mice showed an accumulation of diglycerides, suggesting that additional lipases may be present that can hydrolyze the first ester bond of triglyceridesStill controversial
7 PI3KInsulinPhosphorylatesLPLHydrolyzes triglycerides in the blood to increase FFA levelsPI3KInhibits lipolysis in adipose cellsMediates insulin-stimulated glucose uptakePhosphodiestesterase-3Degrades
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