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1 The cryodenic refrigerator medical equipment and labware Conference name Messe Exhibition Date and Apr. 14-20, 2007 City Hannover, Germany Speakers name.

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Presentation on theme: "1 The cryodenic refrigerator medical equipment and labware Conference name Messe Exhibition Date and Apr. 14-20, 2007 City Hannover, Germany Speakers name."— Presentation transcript:

1 1 The cryodenic refrigerator medical equipment and labware Conference name Messe Exhibition Date and Apr. 14-20, 2007 City Hannover, Germany Speakers name Mostytskij Andrij Telephone +(38044) 424 91 69, +(38044) 426 81 90 E-mail dnipro@public.ua.net Name of institute or company Scientific and Engineering Company Dnipro-MTO Ltd City Kyiv, Ukraina

2 2 Proprietary information statement The technology material presented in this talk is available for licensing or joint product development. None of the slides contain any confidential or proprietary information which would prevent patenting the technology.

3 3 Problem Description & Market Need low temperature refrigerators for freezing and long storage of blood and its components (in particulars storage stem cells - hemopoietic cells - predecessors), donor organs and other biomaterials with a level of cooling up to -90 °C; Scientific and Engineering Company "Dnipro-MTO" LTD develops and produce the following cryogenic equipment: cryosurgical and cryotherapeutic equipment for treatment of oncological and inflammatory diseases within the temperature span from -35 up to -165 °C;

4 4 Problem Description & Market Need histological equipment for express diagnostics of inflammatory oncological diseases. Technology based on one cascade (contour) of cooling and utilizing mixture of refrigerating agents allows us to develop cryogenic refrigerator systems with a level of cooling up to -190 °C with the use of usual household (trading) refrigerating unit (compressor) and without the use of liquid nitrogen. Such approach provides for better reliability, improved effi­ciency and reduced cost price.

5 5 Brief technology description Advantages Scientific and technical characteristics of the developed equipment correspond to the best world famous analogues. At the same time this equipment is efficient, cheaper (in 1,5- 2 times) and simpler in comparison with the cryogenic equipment and apparatuses working on liquid nitrogen, nitrous oxide or others cryoagents. Cryogenic refrigerator systems on mixes of coolants of firm "Dnipro-MTO" work from electric mains, do not demand periodic updating of any cryoagents and are irreplaceable in places where delivery of the liquefied or compressed refrigerating agent is complicated or impossible. Economic efficiency, reliability and rather low cost in comparison with multicascade systems of cooling, traditionally used for reception of cryogenic temperatures. The presence of several cascades (contours) of cooling (3 or 4 cascades) instead of one-cascade cycle on mixes essentially complicates design that causes decrease in reliability and increase in cost. Ecological safety - non-polluting components are used in structure of mixes.

6 6 Stage of development Chemical compounds of mixes of coolants, pneumatic circuits and designs of refrigerating machineries are protected by author's certificates and patents of Ukraine. The following devices are produced: low temperature refrigerators with a level of cooling up to -90 °C; cryosurgical equipment with a level of cooling up to -150°C; cryotherapeutic equipment with a level of temperatures -40°C. During the last 5 years medical institutions are supplied with over 1000 samples of the equipment. Operation has shown qualitative clinical results. Up to 20 % of volume of production is exported to the countries of the Western Europe, the USA and Japan. In the stage of development (experimental and pre-production models): low temperature refrigerators up to -150°C; cryosurgical equipment up to -175°C; cryotherapeutic equipment and test chambers up to -60°C.

7 7 Targeted Market Segment Medicine (surgery, therapy, diagnostics, cryopreservation); Mechanical engineering (climatic tests); The food-processing industry (storage of products).

8 8 Competition Low temperature equipment of "Dnipro-MTO" for long storage of components of blood and other transplants in comparison with the foreign analogues working on liquid nitrogen (such firms as "Custom Bio Systems " USA, "MVE Bio-Medical Division" USA, "Cryo Diffusion " France) is comparable in price and is accessible to any consumer since liquid nitrogen is not necessary for operation. In comparison with multicascade refrigerator refrigerators (for example, such firms as "Revco ", USA and "Sanyo", Japan) "Dnipro-MTO" refrigerators is easier in a design and cheaper in 1.5- 2 times. The cryosurgical equipment It is cheaper in 2-3 times and also accessible to the consumer in comparison with devices on liquid nitrogen or the other cryoagent ("Erbe Cryo", Germany, "SMT", Czech Republic firms) Foreign analogues of cryosurgical equipment of "Dnipro-MTO" with a level of cooling are lower than -120°С without use compressed or liquefied cryoagent are not found. The cryotherapeutic equipment It is cheaper and economical in comparison with analogues abroad ("Cryo Medicin", Germany).

9 9 Competitive Matrix The name of parameter Comparison of ultra low-temperature refrigerators It is offered by the Project MDF-2136 Sanyo, Japan ULT-10140-9 Revco, USA - Holland 1. Temperature in the cooled chamber, С -135 -80-135 -90 -140 2. Volume of the cooled chamber, dm3 200230190 3. Weight, kg280378483 4. Power consumption, кВА 2,83,04,4 5. Cost under condition of delivery СІР Kiyv $7000 - 8000$19120$15500 Table 1 Comparison characteristics ultra low-temperature refrigerators with refrigerating temperature up to a minus 135 С which are made by foreign firms and are offered in Project

10 10 Competitive Matrix The name of parameter Comparison of ultra low-temperature refrigerators It is offered by the Project MDF-1155 AT Sanyo, Japan ULT-10150-9 Revco, USA - Holland 1. Temperature in the cooled chamber, С -150 -100-152 -10 -150 2. Volume of the cooled chamber, dm3 200128190 3. Weight, kg280320374 4. Power consumption, кВА 3,23,44,4 5. Cost under condition of delivery СІР Kiyv $9000 - 10000$21630$18000 Table 2 Comparison characteristics ultra low-temperature refrigerators with refrigerating temperature up to a minus 150 С which are made by foreign firms and are offered in Project

11 11 Opportunities Concept is the creation of joint venture with the Western partner in Ukraine for expansion of volume and assortment of manufacture of medical equipment. Volume of the investment is $7,0 mln. The period of realization of the project is 2.0-2.5 years. The realization will allow to realize to the full research-and-production potential of the enterprise, to raise a level of incomes in 1.7-2.0 times, to open access to the new markets.

12 12 The contact information about foreign firms, "Dnipro-MTO" cooperates with: 1."MPW Med. instruments" 46, Boremlowska Str., 04-347 Warsaw, Poland Phone: (+4822) 6105621, fax: (+4822) 6108101, E-mail: mpw@mpw.plmpw@mpw.pl Contact person: Tadeusz Gaszczynski, President (cooperation in manufacture of a laboratory centrifuge). 2."Enpol S.A." 19 D1, Mostowa Str., 61-854 Poznan, Poland Phone: (+4861) 8534005, fax: (+4861) 8501146, E-mail: antoni@enpol.com.plantoni@enpol.com.pl Contact person: Antoni Citkowicz, President (cooperation in manufacture of low temperature refrigerators). 3."FRIGERA 21, a.s" 110, Zengrova, 28059 Kolin IV, Czech Republic Phone: (+420) 321754459, fax: (+420) 321721477, E-mail: jaros@frigera.czjaros@frigera.cz Contact person: Radek Jaros, Managing Director (cooperation in manufacture of fast freezers).

13 13 The contact information about foreign firms, "Dnipro-MTO" cooperates with: 4. "Danisevsky s.r.o." 987, Hegerova, 57201 Policka, Czech Republic Phone/Fax: (+420) 461724219, E-mail: Boris.Danisevsky@danisevsky.czBoris.Danisevsky@danisevsky.cz Contact person: Boris Danisevsky, General Manager (joint of equipment for clean gases by laboratory facilities). 5."Uniphy Electromedicin GmbH", 19b, Neuendorfstrabe, 161 761 Hennigsdorf, Germany Phone: (+49) 3302504422, fax: (+49) 330250442299, E-mail: Rainer.Tostmann@uniphy-elmed.comRainer.Tostmann@uniphy-elmed.com Contact person: Rainer Tostmann, General Manager (joint manufacture of cryotherapeutic equipment). 6. Elcold Frysere Hobro ApS Logstorvej 81 Horby DK-9500 Hobro Phone:(+45) 9657 2222, fax: (+45) 9852 4685 E-mail: j.svensson@elcold.comj.svensson@elcold.com Contact person: John Svensson, Area Sales Manager (cooperation in manufacture of fast freezers).


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