2. Ministery of Mexico Health
A major program to control rabies in Mexico was initiated in 2000
Ministery of Mexico Health
Dr. Carlos H. Álvarez Lucas
Mayo, 2007

3. Antecedents
Rabies in dogs was unknown in the Americas before the arrival of the Spanish “conquistadores”.
The first mention of rabies in Mexico is in the Inquisition papers, with two manuscripts of the early 18th century, in which a priest writes that “happy was New Spain while it was still free of the disease of rabies…”.

4. Rabies program
Up until the middle 1980s rabies in animals and, in turn, in humans, changed little from year to year. 31 41 49 64 60 47 78 91 72 54 57 9 69 5 82 2 62 43 18 20 11 15 8 3 6 1 10 30 40 50 70 80 90
100 39 42 45 48 51 63 66
*72 75 81 84 87 93 96 99 02 05
Years
Dog
Other
Species *
Available
1972 -
Figure 1
Human Rabies Deaths in Mexico, 1939 –
2005
When one looks at the figures they remain virtually unchanged: anywhere from 3,000 to 6,000 cases in animals, with over 95% in dogs, and human deaths a year.

5. The program of ‘mass vaccination’ began in 1990 in Mexico.
Rabies program
As has been the case in other countries, canine rabies began to be controlled once the decision was been made to vaccinate enough dogs. 5
Millions
16.6 3
4.1
3.7
3.8
2.7
6.4
4.4
4.9
4.2
5.5
4.3
6.3
5.7
5.2
6.6
4.1
0.4
8.1
3.3
1.25
9.1
2.8
1.4
9.7
2.4
1.6
10.6
2.7
10.4
2.2
11.5
2.5
2.6 3 12
2.3 1 2 4 5 6 7 8 9 10 11 13 14 15 16 17
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
National Vaccination Week
Permanent Program
Additional Reinforcement
7.1
16.0
Figure 2
Rabies
Vaccination in
Dogs ,
Mexico
, 1990 -
The program of ‘mass vaccination’ began in 1990 in Mexico.

6. Rabies program
The number quickly dropped almost to zero or disappeared completely All but 5 of the remaining states have now succeeded in virtually eliminating the endemic disease in dogs; of these five, one is a tropical peninsula (Yucatán).
Figura 3: States Free of Canine Rabies, México,
1995
2005
1990
2000
States whitout rabies

7. Rabies program
Cases of rabies in animals fell during this period, almost in direct relation to the number of dogs vaccinated, human rabies, too, fell to almost nil.
7.1
7.5
9.1
9.3
9.7
10.6
10.9
11.1
12.6
13.3
13.7
14.9
15.9
16.2 16
16.6 45
110
117
244
317
335
523
852
1387
2253
2106
3049
1382
1600
105 76 2 4 6 8 10 12 14 18
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
500
1000
1500
2500
3000
3500
Dogs
Vaccinated (
Millions )
Rabies
Cases
Figure 4
Rabies Cases in
and
Canine
Vaccination ,
Mexico
, 1990 -
7.1
7.5
9.1
9.3
9.7
10.6
10.9
11.1
12.6
13.3
13.7
14.9
15.9
16.2 16
16.6 2 1 3 7 20 15 22 45 29 60 19 4 6 8 10 12 14 18
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005 30 40 50 70
Figure 5
Rabies in
Humans ,
and
Canine
Rabies
Vaccination
Mexico
, 1990 -
Dogs
Vaccinated (
Millions )
Rabies Cases

8. Rabies program Figure 6 Identification of Canine and Feline Rabies
Variants
by Monoclonal
Antibodies
, 1996 -
2005 V -
7 (2)
cat 1 V -
11 (1) dog
dog 1
140
Isolates V -
1 (1) V -
1 (1) V -
8 (1)
cat
cat
cat V -
1 (5)
cat 2 V -
9 (1)
cat
dog 3 1 1 V -
11 (1)
cat V -
10 (1) V -
1 (4) dog
cat V -
8 (1)
cat V -
1 (42)
dogs
40, 5 1 3 3 2
cats 2 2 5 V -
11 (1) dog 1 1 V -
9 (1)
cat 42 3 3 V -
1 (10)
dogs V -
1 (4) 4 4
dogs 3, V -
1 (3)
dog 3 6 6 V -
1 (5)
cat1 1 1
dogs 1 1 42 V -
8 (1)
cat 8 8 4 4 6 6
Variants V -
1 (1)
No.
dog V -
1 Dog
D 120, C 7 V -
1 (1) dog V -
1 (3) dog V - 5
Vampire
D 1 V -
5 (1) do V -
1 (8) 3 V -
1 (6)
dogs 6 V -
1 (28)
dogs 28 V - 7
Grey
Fox
D 1, C 1
dogs 8 V - 8
Skunk
C 3 V -
11 (1)
dogs V -
1 (4)
dogs 4 V -
9 Bat
D1, C1 V -
1 (1) dog V - 10
Skunk
C 1 V - 11
Vampire
D2, C 2

9. Rabies program Figure 7 Identification of Human Rabies Isolates by
Monoclonal
Antibodies
, 1996 -
2005 V -
A (2)(V - 1) 21
Isolates V -
9 (1) 2 2 V -
10 (2) V -
1 (1) 1 2 2 2 1 V -
1 (1) V -
3 (1) 2 2 V -
5 (1)
Variants
No. V -
1 (2) V -
11 (1) V -
1 Dog 7 V - 3
Vampire 1 V -
4 bat 1 1 1 V -
4 (1) V - 5
Vampire 1 V -
A (V -
8 (2)) V - 8
Skunk 2 V -
9 Bat 1 V -
1 (1) V - 10
Skunk 2 V -
1 (1) V - 11
Vampire 4 V -
11 (2) V -
1 (1) V - A
Atypical 2
V11 (1)

10. Comunication strategies evolution
Rabies program
Comunication strategies evolution
Dr. T. Canto
Canuto Perrón
Gatalina Cat

11. Rabies program Conclusions
The canine rabies in Mexico was a problem of public health.
Only country that makes national intensive days of canine antirabies vaccination.
Leader in reduction of canine rabies cases and humans cases transmitted by dog.
Uses biological antirabies humans and canine of the same quality like the countries of the first world.
The use of new technologies alerts the presence of the wild animal rabies.