20 Omega-6 fatty acids and mammary tumors Nb of tumorsDays post graftCarroll et al, 1975 Cancer Res.
21 Advanced Breast Cancer Gago-Dominguez et al., 2003 Brit J Ca – Singapore Prospective women
22 Membrane Protection Neurones exposed to beta-amyloid Neurones without anythingNeurones with omg3 exposed to beta-amyloidNeurones with omg3Florent et al. Jal. Neurochem., 2006
23 Prevention: Framingham Study RR=0.53Schaefer et al, Arch Neurol.
24 Treatment: Omega-3 AD Study PlaceboFreund-Levi et al, 2006 Arch Neurol.
25 Studer et al, Arch Int. Med. 2005 Statins or Omega-3s?Cardiac Mortality-22%-32%Studer et al, Arch Int. Med. 2005
26 Studer et al, Arch Int. Med. 2005 Statins or Omega-3s?All Cause Mortality-13%-23%Studer et al, Arch Int. Med. 2005
27 Flaxseed Project 5% flax seed in animal feed Meat, butter, eggs, cheese, milk balanced in omega-3s Impact on human biological parameters(INRA, CHU Rennes, CHU Lorient)
28 Childhood Cancers - Europe Steliarova-Foucher et al., Lancet
29 Organic vs Conventional Food 42 children 2 to 5 yo - Seattle, Wash« organic » children below EPA safety limit« conventional » children 4 x aboveCurl et al., 2003 Env. Health. Persp.
30 SummaryMany scientifically sound “complementary” and environmental approachesWhich is the best medicine? Which is more “scientific”?No patent = no profits = no awareness
31 Sent: Thur. 02/28/08 5:40 pm To: XXX Great. Thanks Sent: Thur. 02/28/08 5:40 pm To: XXX Great. Thanks. G is a great guy, say hi, and I will keep looking out for the good science he does. Even so, the chances of commercial success hinge on the patent life of a molecule, and we have our hands full with stuff that has that sort of potential. Best, XXX Clinical Director, XXX
32 New Research Orientations 1. “Natural”/sustainable treatments2. “Intellectual property” protection3. Environmental interventions