1. 1 Common names of some popular alcohols

2. 2 Sterically hindered Harder to solvate Easier to solvate Strong inductive effect Stabilizes alkoxide ion More polarizable sulfer ‘Normal’ O-H pka Stability of Resonance structures

3. 3

4. 4

5. 5

6. 6 Limitations of the Grignard Reagent: They react with almost anything, therefore you can’t have the below functional groups on your alkyl halide.

7. 7 Converting an alcohol into a tosylate. (this turns the oxygen of the alcohol into a good leaving group)

8. 8

9. 9

10. 10 Example of Phenols

11. 11

12. 12 Spectroscopy of Alcohols and Phenols Characteristic O–H stretching absorption at 3300 to 3600 cm  1 in the infrared Sharp absorption near 3600 cm -1 except if H- bonded: then broad absorption 3300 to 3400 cm  1 range Strong C–O stretching absorption near 1050 cm  1 (See Figure 17.11) Phenol OH absorbs near 3500 cm -1

13. 13

14. 14

15. 15 NMR of an alcohol

16. 16 -18 g/mol -31 g/mol