Presentation on theme: "Control #A A5 2 wk p.i. Brain Spleen A2 12 wk p.i. Sakuma et al., Supplementary Fig. S1 Fig. S1 Immunostaining of brain and spleen sections with goat anti-gp70/gp30."— Presentation transcript:
Control #A A5 2 wk p.i. Brain Spleen A2 12 wk p.i. Sakuma et al., Supplementary Fig. S1 Fig. S1 Immunostaining of brain and spleen sections with goat anti-gp70/gp30 antibody (green). Nuclei were counterstained with DAPI (blue). Immunostaining images of XMRV-infected animals at 2 wk and 12 wk p.i. were compared with those of the control mouse #A.
N1N2Control CD3/CD11b CD19 CD3/Gr-1 A2 Sakuma et al., Supplementary Fig. S2 Fig. S2 Immunohistochemical analyses of immune cells in spleens of XMRV- infected and uninfected mice. Spleen sections were analyzed with anti-CD3, CD11b, CD19, and Gr-1 antibodies to detect T cells, macrophages, B cells, and neutrophils, respectively. Representative immunostaining results for control mice and XMRV infected mice (A2, N1, N2) were shown. Nuclei were counterstained with DAPI (blue).
Sakuma et al., Supplementary Table 1 a WBC, LYM, NON, GRA, RBC, HGB, HCT, MCV, MCH, MCHC, and PLT represents white blood cell, lymphocyte, monocyte, granulocyte, red blood cell, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and platelet, respectively. b Numbers outside of the 95% reference range are highlighted. C1C2C3C4C5C6C7C8C9C10C11C12 (wk 30) (wk 28) (wk 11) (wk 7) WBC a 6.177.346.936.517.058.634.814.7220.127.116.11.06 LYM4.775.514.474.655.155.093.613.35 b 4.84.754.315.07 MON0.170.150.120.080.190.210.280.220.040.070.290.2 GRA1.231.682.341.781.713.320.921.21.371.411.31.78 RBC10.95 10.5910.858.3910.6510.0710.7110.7510.9310.5411.48 HGB17.217.417.216.913.417.615.716.915.717.717.217.7 HCT47.1446.8947.146.3335.1745.2541.9545.3942.3746.7546.5147.53 MCV43 444342 39434441 MCH15.715.916.215.516.016.515.615.814.616.216.315.4 MCHC36.437.036.4 38.138.837.437.337.137.937.037.2 PLT626721175344688703885826814580622737 Average ± 1.96 STDV 4.4-8.6 3.4-5.9 0.01-0.32 0.4-2.9 9.1-12.1 14.3-19.2 38-52 40-45 14.8-16.8 35.8-38.7 244-1042 Supplementary Table 1. Summary of CBC test results for uninfected Mus pahari