1. Working with USAMRIID A Science Expedition on Epidemics and Viruses Grade 7; GLE 23

2. Your Challenge! The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) has created a walking tour in order to have visitors better understand how viruses work and how we fight them!USAMRIID You have just been hired to lead the walking tour through the USAMRIID offices in Fredrick, Maryland. Before you can conduct your first tour, it is important that you understand all about viruses yourself! In order to prepare, USAMRIID is requiring that you complete the following science expedition. Good Luck!

3. Phase 1: Create Your Employee Badge USAMRIID is a highly secure institution. Before you can explore the different levels of the building you will need to create your employee badge. Use a digital camera to take your picture and complete the information below. Place Your Photo Here Tour Guide CONTINUE

4. Phase 2: What is USAMRIID? Your first challenge is to understand what USAMRIID does and learn about the history of the organization. Begin by viewing the video below! Note: You will need your LPB Streaming Username and Password. View Video Segment: USAMRIID: The U.S. Army Medical Research Institute of Infectious Disease (03:07) CONTINUE

5. Understanding USAMRIID’s History… Use the following website, http://www.usamriid.army.mil/highlightspage.htm to choose four events in the history of USAMRIID that you find most interesting to share with tour participants.http://www.usamriid.army.mil/highlightspage.htm Type information in boxes! CONTINUE

6. Phase 3: Understanding Terminology Use one of the following resources to complete find the correct definition for the virus terminology below: Epidemics and Plagues by Richard Walker World Book Encyclopedia: http://www.doe.state.la.us/worldbook/http://www.doe.state.la.us/worldbook/ Ebsco: http://search.ebscohost.com/ (Username: student Password: ebsco)http://search.ebscohost.com/ Merrian-Webster Online Dictionary: http://www.m-w.com/http://www.m-w.com/ antibiotic bacteria cell contagious epidemic CONTINUE

7. Understanding Terminology Continued immunity infectious disease pandemic vaccination virus CONTINUE

8. Phase 4: Understanding the Equipment Used to View Viruses Scientist at USAMRIID use microscopes to view the organisms that cause viruses since they are not visible with the naked eye. In this phase, you will use your digital microscope to view objects at different magnifications. Materials: one small piece on an onion layer, tweezers, iodine, slide, digital microscope The Experiment: 1.Place a small piece of onion skin onto a slide. 2.Place a small drop of iodine on the onion skin. Make sure that the onion skin is laying flat. 3.Use the digital microscope to take photograph of the onion skin at the following magnifications: 10X, 60X, and 200X. 4.Place your results on the next slide. CONTINUE

9. Magnification of an Onion Skin Sample 10X Magnification60X Magnification200X Magnification CONTINUE

10. What do you notice about the onion skin specimen as the magnification increases?

11. Epidemics and Viruses: Yellow Fever Throughout history many epidemics were caused by viruses. On the next slides use the provided Internet reference to investigate viruses and the resulting epidemics… Yellow fever virus (234,000x magnification). How is yellow fever transmitted? What are the symptoms of yellow fever? Center for Disease Control Yellow Fever Website: http://wwwn.cdc.gov/travel/yellowBookCh4-YellowFever.aspx http://wwwn.cdc.gov/travel/yellowBookCh4-YellowFever.aspx Where do most cases of yellow fever occur today and how might it be prevented? CONTINUE

12. Epidemics and Viruses: Polio Polio Viruses What is the cause of polio? What are the symptoms of polio? Mayo Clinic Website: http://www.mayoclinic.com/health/polio/DS00572/DSECTION=2 http://www.mayoclinic.com/health/polio/DS00572/DSECTION=2 How is polio treated today? CONTINUE

13. Epidemics and Viruses: The Bubonic Plague Yersinia pestisYersinia pestis seen at 2000x What is the cause of bubonic plague? What are the symptoms of the bubonic plague? CDC Plague Website: http://www.cdc.gov/ncidod/dvbid/plague/ http://www.cdc.gov/ncidod/dvbid/plague/ Who is at risk of contracting the plague today? CONTINUE

14. Epidemics and Viruses: Smallpox What is the cause of smallpox? What are the symptoms of smallpox? US Department of Health and Human Services Website: http://www.smallpox.gov/#basics http://www.smallpox.gov/#basics Where are cases of smallpox found today? CONTINUE

15. Epidemics and Viruses: Ebola What is the cause of Ebola? What are the symptoms of Ebola? Center for Disease Control Website: http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/ebola/qa.htm http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/ebola/qa.htm Where are most cases of Ebola found today? CONTINUE

16. Congratulations! You have completed all the phases in preparation for you new job… You have one more thing to do before you can begin your first tour. Create a one- paragraph introduction which outlines what you will say to introduce your tour concerning viruses.

17. Teacher’s Page Lesson Title: Working with USAMRIID Subject: Science 7 Brief description of Lesson (1 paragraph): In this lesson the students will explore the aspects of viruses and epidemics utilizing the digital camera, digital microscope, and the Internet. Lesson GLE(s): 23 Materials Needed (including electronic templates): MSPowerPoint, Internet, digital camera, digital microscope Name: Tammy S. Seneca Email Address: tseneca@wbrschools.k12.la.ustseneca@wbrschools.k12.la.us