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Published byAva Riley
Modified over 3 years ago
Personal Genetics A Self-Discovery Platform
© 23andMe, Inc.2 Personal Genetics--Why Now? People want to know Information is empowering Genetics research + community = more power Whole genome sequencing is coming Education is key
© 23andMe, Inc.3 Personal Genome Service Launched Nov 2007 ~600K genotypes generated per customer From 14 to over 100 reports –Research Reports/Clinical Reports Added survey tools Added community feature –Over 1000 conversation threads Moved to second generation array Launched research platform (23andWe)
© 23andMe, Inc.4 v2 Custom Content Ancestry markers (Y and Mito coverage) DMET for PGx-focused studies Rare mutations for carrier status –BRCA, LRRK2, Cystic Fibrosis, etc. HLA coverage for immune system SNPs of interest published in recent GWAS studies Launched research platform (23andWe)
© 23andMe, Inc.5 Genomic Cloud Computing
© 23andMe, Inc.6 Genome Canvas
© 23andMe, Inc.7
© 23andMe, Inc.10 Identical Half-identical Different Siblings
Health and Traits
© 23andMe, Inc.12
© 23andMe, Inc.13 Crohns Disease Risk
© 23andMe, Inc.14 Crohns Disease Risk
© 23andMe, Inc.15 Crohns Disease (50-60% Genetics Risk)
Personal Genetics A Research Platform
© 23andMe, Inc.17
© 23andMe, Inc.18 23andWe Surveys
© 23andMe, Inc.19 Parkinsons Study
Personal Genetics A Translational Platform
© 23andMe, Inc.21 New: Warfarin PGx Report Goal: Build large community of patients on warfarin, track INRs, develop evidence base for genetic data, find additional markers.
© 23andMe, Inc.22 PGSPHR Research Data EMR Healthcare Consumer CliniciansHospitals Validated Data Testing Labs Patient-Centric Health Data
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1 Copyright © 2010, Elsevier Inc. All rights Reserved Fig 2.1 Chapter 2.
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Immunobiology: The Immune System in Health & Disease Sixth Edition
Copyright © 2011, Elsevier Inc. All rights reserved. Chapter 5 Author: Julia Richards and R. Scott Hawley.
Squares and Square Root WALK. Solve each problem REVIEW:
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