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Personal Genetics A Self-Discovery Platform
© 23andMe, Inc.2 Personal Genetics--Why Now? People want to know Information is empowering Genetics research + community = more power Whole genome sequencing is coming Education is key
© 23andMe, Inc.3 Personal Genome Service Launched Nov 2007 ~600K genotypes generated per customer From 14 to over 100 reports –Research Reports/Clinical Reports Added survey tools Added community feature –Over 1000 conversation threads Moved to second generation array Launched research platform (23andWe)
© 23andMe, Inc.4 v2 Custom Content Ancestry markers (Y and Mito coverage) DMET for PGx-focused studies Rare mutations for carrier status –BRCA, LRRK2, Cystic Fibrosis, etc. HLA coverage for immune system SNPs of interest published in recent GWAS studies Launched research platform (23andWe)
© 23andMe, Inc.5 Genomic Cloud Computing
© 23andMe, Inc.6 Genome Canvas
© 23andMe, Inc.7
© 23andMe, Inc.10 Identical Half-identical Different Siblings
Health and Traits
© 23andMe, Inc.12
© 23andMe, Inc.13 Crohns Disease Risk
© 23andMe, Inc.14 Crohns Disease Risk
© 23andMe, Inc.15 Crohns Disease (50-60% Genetics Risk)
Personal Genetics A Research Platform
© 23andMe, Inc.17
© 23andMe, Inc.18 23andWe Surveys
© 23andMe, Inc.19 Parkinsons Study
Personal Genetics A Translational Platform
© 23andMe, Inc.21 New: Warfarin PGx Report Goal: Build large community of patients on warfarin, track INRs, develop evidence base for genetic data, find additional markers.
© 23andMe, Inc.22 PGSPHR Research Data EMR Healthcare Consumer CliniciansHospitals Validated Data Testing Labs Patient-Centric Health Data
DIYgenomics: an open platform for citizen science Melanie Swan Founder DIYgenomics
Biomarker Based PGx Strategies Rick Hockett, MD Chief Medical Officer Affymetrix.
25 seconds left….. 24 seconds left….. 23 seconds left…..
Public Being Streetwise with MT in an Enterprise Neighborhood Will Burgett, PMP® Product Manager Translation Innovation & Services Marketing Solutions.
1. 2 Better Prevention and Management of Chronic Disease are Critical to Improving Health Outcomes and Lowering Healthcare Costs Source: DeVol, R, Bedroussian,
Addition 1’s to
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The Human Genome Project. What is the Human Genome Project? -U.S. govt. project coordinated by the Department of Energy and the National Institutes of.
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