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Personal Genetics A Self-Discovery Platform
© 23andMe, Inc.2 Personal Genetics--Why Now? People want to know Information is empowering Genetics research + community = more power Whole genome sequencing is coming Education is key
© 23andMe, Inc.3 Personal Genome Service Launched Nov 2007 ~600K genotypes generated per customer From 14 to over 100 reports –Research Reports/Clinical Reports Added survey tools Added community feature –Over 1000 conversation threads Moved to second generation array Launched research platform (23andWe)
© 23andMe, Inc.4 v2 Custom Content Ancestry markers (Y and Mito coverage) DMET for PGx-focused studies Rare mutations for carrier status –BRCA, LRRK2, Cystic Fibrosis, etc. HLA coverage for immune system SNPs of interest published in recent GWAS studies Launched research platform (23andWe)
© 23andMe, Inc.5 Genomic Cloud Computing
© 23andMe, Inc.6 Genome Canvas
© 23andMe, Inc.7
© 23andMe, Inc.10 Identical Half-identical Different Siblings
Health and Traits
© 23andMe, Inc.12
© 23andMe, Inc.13 Crohns Disease Risk
© 23andMe, Inc.14 Crohns Disease Risk
© 23andMe, Inc.15 Crohns Disease (50-60% Genetics Risk)
Personal Genetics A Research Platform
© 23andMe, Inc.17
© 23andMe, Inc.18 23andWe Surveys
© 23andMe, Inc.19 Parkinsons Study
Personal Genetics A Translational Platform
© 23andMe, Inc.21 New: Warfarin PGx Report Goal: Build large community of patients on warfarin, track INRs, develop evidence base for genetic data, find additional markers.
© 23andMe, Inc.22 PGSPHR Research Data EMR Healthcare Consumer CliniciansHospitals Validated Data Testing Labs Patient-Centric Health Data
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1 Copyright © 2010, Elsevier Inc. All rights Reserved Fig 2.1 Chapter 2.
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Immunobiology: The Immune System in Health & Disease Sixth Edition Chapter 14 Manipulation of the Immune Response Copyright © 2005 by Garland Science Publishing.
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Copyright © 2011, Elsevier Inc. All rights reserved. Chapter 5 Author: Julia Richards and R. Scott Hawley.
Squares and Square Root WALK. Solve each problem REVIEW:
ABC Technology Project Mrs. Kiddle. ABCs of Technology Word 1 Word 2 Word 3 Word 4 Word 5 Word 6 Word 7 Word 8 Word 9 Word 19 Word 20 Word 21 Word 22.
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Immunobiology: The Immune System in Health & Disease Sixth Edition Chapter 11 Failures of Host Defense Mechanisms Copyright © 2005 by Garland Science Publishing.
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Chapter 13 How Cells Obtain Energy from Food Essential Cell Biology Third Edition Copyright © Garland Science 2010.
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MULT. INTEGERS 1. IF THE SIGNS ARE THE SAME THE ANSWER IS POSITIVE 2. IF THE SIGNS ARE DIFFERENT THE ANSWER IS NEGATIVE.
© Charles van Marrewijk, An Introduction to Geographical Economics Brakman, Garretsen, and Van Marrewijk.
1 Welcome to Seminar Unit 9: Analysis of an Optimum Model of Health and Wellness Robyn Hoban.
Slide 1 Advanced Piloting Cruise Plot. Advanced Piloting Cruise United States Power Squadrons ® Part I Question 1 Question 2 Question 3 Question 4 Question.
TWO STEP EQUATIONS 1. SOLVE FOR X 2. DO THE ADDITION STEP FIRST
SUBTRACTING INTEGERS 1. CHANGE THE SUBTRACTION SIGN TO ADDITION 2. TAKE THE INVERSE OF THE SECOND NUMBER 3. FOLLOW THE RULES FOR ADDITION 4. ADD THE OPPOSITE.
A SMALL TRUTH TO MAKE LIFE 100%. If A B C D E F G H I J K L M N O P Q R S T U V W X Y Z is equal to
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1 Copyright © 2013 Elsevier Inc. All rights reserved. Appendix 01.
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Year 6 mental test 5 second questions Multiplication and Division Tables knowledge.
My Alphabet Book 2 a b c d e f g h i j k l m n o p q r s t u v w x y z My name is Autumn and I work hard at school.
Subtraction: Adding UP. Category 1 The whole is a multiple of ten.
© 2006, François Brouard Case Real Group François Brouard, DBA, CA January 6, 2006.
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PSSA Preparation. Question 1(no calculator) D Question 2 (no calculator)
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