Presentation on theme: "Overview of HIV/AIDS and ARV Treatment in Georgia"— Presentation transcript:
1 Overview of HIV/AIDS and ARV Treatment in Georgia Lali Sharvadze MD, PhDDirector of inpatient Department .Associated Professor.
2 Reported Cases of HIV/AIDS in Georgia2518AIDS538 - DeathsEstimated number 3500
3 Distribution of HIV/AIDS Patients by Sex and Age Groups2518Women 665Men 1853Age distribution
4 HIV Cases Registered in Georgia Annually Number of cases
5 Distribution of HIV/AIDS Cases (number of registered cases) by Regions of Georgia(number of registered cases)Abkhazia168891Tbilisi(55 Foreigners)Svaneti8Lechkhumi5Samegrelo369Mtianeti19Poti39Imereti319Guria54Shida Kartli66Adjara322Kakheti102SamtskheJavakheti29Kvemo Kartli94
6 Incidence of AIDS Cases per population(Source – WHO reports, 2007)
7 HIV Prevalence among High Risk Behavior Groups (2007) HIV Prevalence in General Population
8 Distribution of HIV Cases by Routes of Transmission
9 AIDS Control Service in Georgia Country Coordinating Mechanism (CCM)Infectious Diseases, AIDS & Clinical Immunology Research CenterNational Center of Disease Control and Public HealthZugdidiAIDS treatment centerBatumiAIDS treatment centerKutaisiAIDS treatment center9 VCT centers in regions of Georgia217 HIV diagnostic labs
10 Universal Access to HIV Treatment, Care and Support and Prevention Georgia is the First AmongFSU Countries that from 2004 Ensured Universal (100%) Access to ARV Treatment.
11 What Does It Mean - The Universal (100%) Access to ARV Treatment Georgian Approach Investigation of all HIV infected personsby special algorithmTo identify all patients requiring ARVtreatment according to special criteriaTo offer ARV therapy to all patientsrequiring treatmentMonitoring of all patients receiving ARV treatment
12 according to WHO/UNAIDS/UNICEF report on universal access of 2008 Access to HAARTRUS*BEL*UKR*KAZ*GEOUZB*KGZ*AZE*ARM*TKMTJK*ALB* FYM*according to WHO/UNAIDS/UNICEF report on universal access of 2008no HAART individuals on HAART (<1%) * in the process of scaling up ARTvery poor access ( 1-25%) poor access (25-50%) disputed coverage estimates orinsufficient data availablemoderate access (50-75%) good access (over 75%)
13 Implementation of Major Laboratory Methods in Georgia1984 – ELISA1984 – Immunophenotyping of CD3, CD4, CD8 lymphocytes1985 – Western blot1995 – Qualitative PCR (Polymerase Chain Reaction)1996 – Quantitative PCR (Polymerase Chain Reaction)2003 – HIV and HCV Genotyping2005 – HIV Genotypic Resistance TestingHIV subtype analysis using phylogenetic methods2006 – HIV, HCV & HBV quantitative- Real time PCR2006 – CCR5, CCR2 and SDF1 genotyping testing2009 – Abacavir hypersensitivity testing HLA-B*5701 SSP genotyping assay.
15 739 Patients are currently receiving ART ARV Treatment739 Patients are currently receiving ART710adults29 children
16 National Guidelines Criteria for Initiation of Antiretroviral Therapy Based on WHO and DHHS ART GuidelinesHistory of an AIDS-defining illness;CD4 T - cell count <350 cells/mm3;Patients with HIV-associated nephropathy;Patients co infected with HBV when treatment is indicated.
17 Georgian HIV/AIDS National Guidelines updated annually