Presentation on theme: "BIOMEDICAL ENGINEERING A New, Promising Interdisciplinary Field"— Presentation transcript:
1 BIOMEDICAL ENGINEERING A New, Promising Interdisciplinary Field Wei R. Chen, Ph.D. Professor Director of Biomedical Engineering Program Department of Physics and Engineering University of Central OklahomaSeptember 13, 2005 UCO Intro to Engineering Class
2 OUTLINE What is Biomedical Engineering BME in US -- current status Professions in BMEJobs for Biomedical Engineering GraduatesBME in US -- current statusThe New BME program at UCOProgram design and curriculumExamples of Research in BMEBiomedical imaging of cancerBiomedical engineering modalities for cancer treatment
3 WHAT IS BIOMEDICAL ENGINEERING Application of engineering skills, principles, and tools to problems in biology, medicine, and health careInterdisciplinary field requiring a unique curriculum that provides students with an understanding of both engineering principles and the life sciences
4 WHAT DO BME STUDENTS LEARN Basic human physiology and functionsHuman biological systems in terms of fundamental physics and engineering principlesBasic chemistry knowledge and laboratory techniquesKnowledge of biomaterials, biomechanics and related fields
5 WHAT DO BME STUDENTS LEARN Latest instrumentation and methodologies in biomedical engineeringUse computers in a biomedical settingResearch experience in biomedical settingsPractical biomedical engineering experience through job-related training, industrial internships, and biomedical design projects
6 WHERE DO BME UNDERGRADUATES GO Professional WorkforceMedical device and process manufacturersMedical research organizationsGovernment medical agencies and hospitalsGraduate SchoolsBiomedical engineeringOther engineering and related disciplinesOther Professional SchoolsMedical, dental, and law
7 JOBS FOR BME GRADUATESdesigning and constructing cardiac pacemakers, defibrillators, artificial kidneys, blood oxygenators, hearts, blood vessels, joints, arms, and legs.designing computer systems to monitor patients during surgery or in intensive care, or to monitor healthy persons in unusual environments, such as astronauts in space or underwater divers at great depth.
8 JOBS FOR BME GRADUATESdesigning and building sensors to measure blood chemistry, such as potassium, sodium, O2, CO2, and pH.designing instruments and devices for therapeutic uses, such as a laser system for eye surgery or a device for automated delivery of insulin.constructing and implementing mathematical/computer models of physiological systems.
9 JOBS FOR BME GRADUATESdesigning clinical laboratories and other units within the hospital and health care delivery system that utilize advanced technology.designing, building and investigating medical imaging systems based on X-rays (computer assisted tomography), isotopes (position emission tomography), magnetic fields (magnetic resonance imaging), ultrasound, or newer modalities.
10 JOBS FOR BME GRADUATESdesigning and constructing biomaterials and determining the mechanical, transport, and biocompatibility properties of implantable artificial materials.investigating the biomechanics of injury and wound healing.
11 JOBS FOR BME GRADUATESimplementing new diagnostic procedures, especially those requiring engineering analyses to determine parameters that are not directly accessible to measurements, such as in the lungs or heart.
12 BIOMEDICAL ENGINEERING IN THE UNITED STATES HistoryStarting in 1960’sJohns Hopkins UniversityCurrent Status117 colleges and universities102 undergraduate degree programs105 master’s degree programs101 doctoral degree programsThe Whitaker Foundation, 2005
13 BIOMEDICAL ENGINEERING IN THE UNITED STATES In the Past Twenty YearsBME Undergraduate EnrollmentUP 200%BME Graduate EnrollmentUP 300%Other Engineering EnrollmentSlightly decline
19 UCO BME GRADUATESGraduate Schools Environment Companies BME Software Applications Other Transitional work
20 NEW BME UNDERGRADUATE PROGRAM AT UCO Business TrendBiotechnology boomingNext major discipline (PRISM, Sept. 1999)EmploymentIncreasing demands (World, U.S. and OK)Important, fulfilling professionHigh paySaving lives
21 BIOTECH INDUSTRY IN OKLAHOMA Early development stageShortage of trained BME personnelLack of undergraduate BME programCompanies leave statesStudents leave states to pursue BME education (to Texas)
22 BME CURRICULUM PROGRAM AT UCO Concentration A: Pre-Medicine Biology: 11 hoursChemistry: 25 hoursEngineering: 39 hoursMath and Computer Science: 14 hoursPhysics: 8 hoursGeneral Ed: 29 hoursTotal: 126 hours
23 BME CURRICULUM PROGRAM AT UCO Concentration B: Bio-Instrumentation Biology: 11 hoursChemistry: 10 hoursEngineering: 45 hoursMath and Computer Science: 14 hoursPhysics: 18 hoursGeneral Ed: 29 hoursTotal: 127 hours
24 BME PROGRAM AT UCO Major Goals Provide Oklahoma students with an opportunity to pursue a BME undergraduate degreePrepare students to pursue a BME doctoral degree at OU Bioengineering Center and OSU Center for Laser and Photonics ResearchEstablish, in collaboration with OU, OUHSC, OSU and health industries, a regional center for BME undergraduate education
25 BME PROGRAM AT UCO Major Goals Facilitate for students with associate degree in BME from community colleges to pursue a BS degree in BMEEstablish collaboration with local biomedical companies for internship and job trainingGraduate at least ten students each year with BS degree in BME, with at least five students continuing BME education in graduate school
26 SUPPORT FOR THE BME PROGRAM AT UCO Support from departments of Colleges of Math and Science at UCOBiologyChemistryComputer ScienceMathematicsPhysics and Engineering
27 SUPPORT FOR THE BME PROGRAM AT UCO Support from External InstitutionsOU Health CenterOU Bioengineering CenterOU Department of Physiology and BiophysicsOU Department of Cell BiologyOSU Veterinary Laser Surgery CenterOSU Sensor Technology Center
28 SUPPORT FOR THE BME PROGRAM AT UCO Support from Oklahoma IndustryUroCorZymeTxWound Healing of OklahomaSoundTechNanomagneticEtc.
29 CURRENT BME COURSES Principle of Biomedical Engineering Introduction to applications of physics and engineering principles to biomedical systemsStudy of biomedical functions of the human body using mechanics, electricity and magnetism, optics, and thermodynamicsResponses of human biomedical functions to different bioengineering applications
30 NEW BME COURSES AT UCO Signals and Control Systems & Lab Signal Analysis in Time DomainSignal Analysis in Frequency DomainSystem ControlsBackground Information and Experiments
31 NEW BME COURSES AT UCO Biomedical Imaging Introduction to applications of physics and engineering principles in medical diagnostics and treatmentMethods and instrumentation in biomedical imaging such as x-ray, MRI, and ultrasound, etc.Biomedical imaging processing
32 NEW BME COURSES AT UCO Biomedical Instrumentation Measurement of analysis of biological systemsComponents of instrumentation:Transducer, circuitsDisplay and analysis of biomedical signalsData acquisition and controlsSafety
33 NEW BME COURSES AT UCO BME Senior Engineering Design I & II Identify design-related projectWritten project proposalTeam workDesign, develop, test, and evaluate projectProject report
34 BIOMEDICAL ENGINEERING – PRODUCE OF SYNERGISM DIFFERENT DISCIPLINESPhysical Sciences – Physics and ChemistryMathematics and ComputerBiological Sciences and MedicineEngineeringDIFFERENT EFFORTSEducationHealth CareIndustry
35 BME RESEARCH AT UCOCancer Treatment Using Selective Photothermal InteractionsDye targeted tissueNoninvasive laser treatmentPhoto Dynamic Immuno Therapy in Treatment of Metastatic TumorsLaserLaser-absorbing dyeImmunoadjuvant
36 BME RESEARCH AT UCO X-Ray Biomedical Imaging Laser-Tissue Interactions Breast cancer detectionImaging guided laser treatmentLaser-Tissue InteractionsEnergy and temperature distributionsExperimentsMonte Carlo simulations
37 EXAMPLES OF RESEARCH ACTIVITIES AT UCO Photo Dynamic Immuno TherapyDye-immunoadjuvant injectionNoninvasive laser irradiationLong-term survivalResistance to tumor rechallengeAdoptive immunity transferTreatment of metastatic tumors
44 BIOMEDICAL ENGINEERING IN RESEARCH Tumor DetectionImaging techniqueTumor localization for injectionDistribution of Drug in TumorTransport phenomenonChemical engineering
45 BIOMEDICAL ENGINEERING IN RESEARCH Laser Energy Delivery-EngineeringDosage calculation and optimizationOptical system for energy deliveryEngineering designThermal Tissue InteractionEnergy and temperature distributionMathematics and computer modeling
46 BIOMEDICAL ENGINEERING IN RESEARCH Optimization of Laser TreatmentLaser parametersDye dose: concentration & volumeImmunoadjuvant dose: concentration & volumeAnti-Tumor Immune ResponseTumor immunologyMolecular biology
47 BIOMEDICAL ENGINEERING IN RESEARCH Interdisciplinary ResearchBiologyChemistryPhysicsEngineeringMathematicsComputer modeling
48 FURTHER INFORMATION ON BIOMEDICAL ENGINEERING Biomedical Engineering HandbookRelated Web Sites:Biomedical Engineering SocietyThe Whitaker Foundation for BMEBME Net
49 FURTHER INFORMATION ON BIOMEDICAL ENGINEERING Related Web Sites:BME Program at Johns Hopkins UniversityBME Program at University of VirginiaBME Program at Texas A&M University