e.g. Neuropathy EventTC … Parathesia32 Parathesia NOS40 Parathesia other01 … Peripheral motor neuropathy60 Peripheral sensory neuropathy32
Other examples Heart failure Separate near synonyms Allocate to heart and lung
Other examples Heart failure Separate near synonyms Allocate to heart and lung Bleeding: distribute over body systems
Consider mechanism If you dont get the drug, you cant react to it Eschew ITT: safety population Modified Daleys Rule: censor early and often Dont collect extraneous information Appeal to statistical conservatism
Populations ITT mITT Safety: one dose of study med ATP Etc.