Presentation on theme: "Prof. S. Shakir Jamil Director General CCRUM, Department of AYUSH"— Presentation transcript:
1Role of Unani Medicine as Adjuvant therapy in Chronic & Incurable Diseases Prof. S. Shakir JamilDirector GeneralCCRUM, Department of AYUSHNew Delhi10th Knowledge Millenium Summit-2013“Curing the Incurables: Sharing of Innovation”16th January, 2013, Vigyan Bhavan, New Delhi
2Origin & Caravan Unani System of Medicine originated from Greece The philosophical doctrines of the System was laid down by Hippocrates. ( BC)Arab, Central Asian and European countries contributed to the system.From Central Asia Unani Medicine traversed to India
3Present ScenarioToday, India is the world leader in Unani Medicine having largest set up of educational, healthcare and research facilities.Unani medicine is also recognized, practiced and popular in Pakistan, Bangladesh, Malaysia, Sri Lanka and South Africa.Also Practiced in Kuwait, Dubai & Saudi Arabia etc.
4Fundamental concepts Tabiyat (Medicatrix naturae) Mizaj (Temperament) Akhlat (Body Humours)Usool-e- Ijaj (Principles of treatment) including Ilaj- bit-Tadbir (Regimenal Therapy)
5Research & Development CCRUMCentral Council for Research in Unani Medicine (CCRUM) was established by Government of India as apex organization for Research and Development activities in Unani System of Medicine in 1979.The Council is an autonomous organization under Department of AYUSH, Ministry of Health & Family Welfare, Govt of India.
8CCRUM - Mandate Research in Unani Medicine on scientific lines. To initiate, aid, develop and coordinate scientific research of Unani Medicine.To finance researches meant for furtherance of objective of the CCRUM.To exchange information with other institutions.To prepare and publish literature on Unani medicine.88
9Research Programmes Pre-clinical/Safety Studies Clinical Research Fundamental aspects of Unani MedicineDrug Standardization including SOPs for Unani drugsLiterature including Medico-historical ResearchEthno-botanical Survey, Collection and Cultivation of Unani Medicinal PlantsIEC and other Research oriented programmes
10Pre-Clinical & Clinical Research Pharmacological action/safety evaluation 22 drugsNumber of diseases clinically studied 22Clinical trials completed drugsNumber of drugs under trial 30
11Validation of Pharmacopoeal drugs Validation of safety & efficacy of Unani pharmacopoeialDrugs.Number of formulations 25Number of diseases under study 10
12Leads in Clinical Research Bars (Vitiligo)Naar-e- Farsi (Eczema)Taqashshur-e-Jild (Psoriasis )Zeequn-Nafas (Bronchial asthma )Zaght-ud- Dam Qawi (Hypertension)Daa-ul-Feel (Filariasis)Iltehaab-e-Mafasil (Rheumatoid arthritis)Iltehaab-e-Tajaweef-e-Aanaf (Sinusitis)
13Validation of Unani Fundamentals Study on susceptibility of acquiring diseases in relation toMizaj (temperament).Study on molecular interpretation of individualtemperament at CRIUM, Hyderabadin collaborationwith Center for Cellular and Molecular Biology, CSIR, Hyderabad.
14Drug Standardization including SOPs for Unani drugs Unani single drugs standardized 298SOPs developed for compound Unani formulations
16Literary ResearchTranslation of classical books/manuscripts in different languages.51Books/brochures/leaflets and IEC material in different languages.25Reprint of rare classical books88Standardization of Unani Terminology4000 terms
17Collaboration/support with other institutions All India Institute of Medical Sciences, (AIIMS) New Delhi.Vallabh Bhai Patel Chest Institute, University of Delhi, New Delhi.Jamia Hamdard (Hamdard University), New Delhi.KGMC, Lucknow.Ibn-e-Sina Academy, Aligarh.Centre of Liver diseases Deccan Med. College, HyderabadTaramani Hospital & Res. Centre, Chennai.Osmania General Hospital Hyderabad.
18Contd.. Collaboration/support with other institutions With the financial support by DST for creating research infra-structure two facilities were created:Clinical Research facilitiy at CRI, Hyderabad.Pre-clinical research facilitiy at RRI, Srinagar.
19Collaboration with Foreign Institutions Centre for Research in Indian Systems of Medicine (CRISM) in University of Mississippi, USAUNANI CHAIR at University of Western Cape, South AfricaUNANI CHAIR at Sri Lanka is in process
20Unani Medicine as Adjuvant therapy Thrust areas:Immuno-modulationTo prevent drug toxicityTo improve Quality of Life
21Unani Medicine as Adjuvant therapy Contd..Unani Medicine as Adjuvant therapyAreasCognitive impairmentTuberculosis (especially MDR TB)CancerHIV / AIDS
22Unani Medicine as Adjuvant therapy Contd..Study 1Cognitive impairmentTitle:Evaluation of a Unani Formulation for Improving Cognitive Impairment in Children with Cerebral Palsy and Mental RetardationThe study was conducted at Majeedia Hospital, Jamia Hamdard in collaboration with UDAAN an NGO working for disabled children.This was a controlled study in which both groups were given physiotherapy and special education but one group was given Unani formulation and other group HBOT.The study was conducted on current clinical parameters following the GCP.Objective:To prove efficacy of Unani formulation in the treatment of Neurodevelopmental disabilities with special emphases on cognitive improvement in Cerebral Palsy (C.P.) and/or Mental Retardation (M.R.).Outcome:Long term amelioration of associated behavioural and neurological problemsImprovement in memory and cognitive functionsImprovement in musculo-skeletal deformities
23Unani Medicine as Adjuvant therapy Contd…Study 2Title:Study on management of Pulmonary Tuberculosis with herbal Unani product (0394) as an adjuvant drug .The study was sponsored by Panacea Biotech and conducted at Majeedia Hospital, Jamia Hamdard, Hamdard Nagar, New Delhi.This was a controlled study in which ATT was given to both groups and only one group was given Unani adjuvant formulation along with ATT.The study was conducted on current clinical parameters following the GCP.Objective:To evaluate the efficacy of Unani formulation in enhancement of resolution rate in Pulmonary Tuberculosis including MDR.Outcome:Fast resolution of infiltration in chest.Faster sputum clearance for AFB.Better response in MDR cases.
24Unani Medicine as Adjuvant therapy Contd…Unani Medicine as Adjuvant therapyStudy 3Title:Clinical evaluation of a Unani formulation for prevention ofhepato-nephro toxicity in Pulmonary Tuberculosis.(The study was conducted at Majeedia Hospital, Jamia Hamdard.This was a controlled study in which both groups were given ATT and one group was Unani Hepato-protective formulation.The study was conducted on current clinical parameters following the GCP.Objective:To evaluate efficacy of Unani formulation in the treatment of Pulmonary Tuberculosis with reference to prevention of hepato-nephro toxicity.
25Unani Medicine as Adjuvant therapy Contd…Unani Medicine as Adjuvant therapyCancerObjective of the study is to prevent the hepato-nephro toxicity during chemotherapy and to improve the Quality of Life in Cancer patients.Feasibility study has been completed. Detailed planning and protocol designing at CRIUM, Lucknow is under progress.
26Unani Medicine as Adjuvant therapy Contd…Unani Medicine as Adjuvant therapyHIV / AIDSObjective of the study is to improve, enhance and potentiate body immunity and to improve the Quality of Life in HIV/AIDS patients.Feasibility study has been conducted. Detailed planning and protocol designing at RRIUM, Mumbai in collaboration with J.J. Hospital, Mumbai.