2 Mitosis - the division of the nucleus into two equal sets of genetic information Basically, simple cell division
3 Mitosis is part of the Cell Cycle The cell cycle is divided into 5 phases.1. Interphase2. Prophase3. MetaphaseMitosis4. Anaphase5. Telophase**This is a moving, continuous process. Stages are for study.
4 Period of growth and normal cell activity InterphasePeriod of growth and normal cell activityEvents of Interphase:90% of the cell life.DNA is in the form of chromatin.DNA replicates, making two exact copies of each chromosome.2 centrioles appear.Stages of interphase:G1 (Gap 1) – normal cell growthS (Synthesis) – DNA synthesis (replication)G2 (Gap 2) – prepares for cell division
6 Mitosis: Prophase Three things happen: Chromatin coils and become visible chromosomes.The nuclear membrane breaks down and disappearsThe spindle fibers & centrioles forms
7 Mitosis: ProphaseLook for chromosomes in the center
8 Mitosis: MetaphaseChromosomes line up on the “equator” (in the middle of the cell)Chromatids attach to the spindle fibers at the centromere
9 Mitosis: MetaphaseLook for chromosomes lined up on the “equator”
10 Mitosis: AnaphaseChromosomes pull apart in opposite directions towards the “poles”This phase ends when the chromosomes reach the poles.
11 Mitosis: AnaphaseLook for chromosomes in two groups pulling apart
12 Mitosis: Telophase The fourth and final phase of mitosis The opposite of ProphaseChromosomes unwind to form chromatinTwo new nuclei form with new membranesThe spindle disappears
13 Mitosis: TelophaseLook for two groups of chromosomes with a cell plate or cleavage furrow
14 Cytokinesis The division of the cytoplasm Animal cells pinch inward forming a cleavage furrow.Plant cells divide from the inside towards the outside by forming a cell plate which becomes the cell wall.