We think you have liked this presentation. If you wish to download it, please recommend it to your friends in any social system. Share buttons are a little bit lower. Thank you!
Presentation is loading. Please wait.
Published byDanielle Morris
Modified over 2 years ago
Kui Xiang 1, GuangTang Pan 1, Lana M. Reid 2, ZhiMing Zhang 1 and XiaoYang Zhu 2 A meta-analysis of QTL associated with ear rot resistance in maize Introduction © Maize Research Institute, Sichuan Agricultural University, Yaan , Sichuan, P.R. China 2 Eastern Cereal and Oilseed Research Centre, Agricultural & Agri-Food Canada, Ottawa, Ontario, Canada K1A 0C6 Maize ear rot (ER) is one of the most prevalent types of maize disease worldwide. The three predominant ER diseases, Aspergillus ear rot (AER), Fusarium ear rot (FER) and Gibberella ear rot (GER), are responsible for the most disease-related reductions in yield and quality. Meta-analysis is a set of statistical procedures for synthesizing research results from a number of different studies. Many studies showed that QTL meta-analyses can be used to combine results from independent published QTL studies. Results and discussion Materials and methods Fourteen studies on maize ER QTL published from were used in the current study. In these studies, the resistance of maize was measured by kernels exhibiting visible symptoms that were converted to percent of infection such as rot and mycelial growth. QTL identified in one population evaluated in a given environment were defined as an experiment. The identified QTL were projected onto a reference map for meta-analysis. The original map position, logarithm of odds score, confidence interval and R 2 (% phenotypic variance explained by the given trait) of each QTL were used for projection. Information pertaining to all genetic maps was collected or estimated according to the published maps, then QTL in their original maps were projected on IBM2 neighbors 2008 (Intermated B73×Mo17 Map) using BioMercator v 2.1 (Arcade et al. 2004). Some controversial markers between original and reference maps were deleted from the analysis to ensure the accuracy of the projection (Chardon et al. 2004). Eighty-seven initial QTL were used in the meta-analysis, which resulted in 29 consensuses ER meta-QTL (MQTL) comprising 65 initial QTL and 22 remaining individual QTL. All these MQTL occurred on all chromosomes with the exception of chromosomes 9 and 10, with two to six initial QTL on each chromosome (Table 1). Ten MQTL pooled three initial QTL, while 13 MQTL pooled two initial QTL. References Arcade A, Labourdette A, Falque M, Mangin B, Chardon F, Charcosset A, Joets J (2004) Biomercator: Integrating genetic maps and QTL towards discovery of candidate genes. Bioinformatics 20:2324–2326 Chardon F, Virlon B, Moreau L, Falque M, Joets J, Decousset L, Murigneux A, Charcosset A (2004) Genetic architecture of flowering time in maize as inferred from quantitative trait loci meta-analysis and synteny conservation with the rice genome. Genetics 168:2169–2185 ER in maize is mainly associated with three types (AER, FER and GER) based on the pathogen causing the ear rot. From meta-analysis, most MQTL consisted of two or three types of ER resistance. Eleven of 29 MQTL contributed to both FER and GER on chromosomes 1 to 7, especially on chromosomes 2 and 3, suggesting that there were some common QTL/genes for FER and GER resistance in these regions. Based on 29 MQTL, a total of 21 genes were found to be co- located within 2 cM of identified MQTL positions, located on 13 MQTL (1, 3, 4, 8, 10, 11, 14, 15, 16, 21, 22, 25 and 26). MQTLChrom.Number of Projected QTL Type of ER a MQTLChrom.Number of projected QTL Type of ER a 112FER, GER1652FER 212FER, GER1753FER, GER 312GER1853AER, FER, GER 423FER, GER1962FER 523FER, GER2062FER 623FER, GER2162FER,GER 733AER, FER2262FER 836FER, GER2362AER, FER 936AER, FER, GER2472FER 1032AER, FER2572FER, GER 1133AER, FER, GER2673FER, GER 1233AER, FER, GER2773GER 1345AER, FER2874GER AER, FER29 82 FER 1544FER, GER Table1 Characteristics of detected meta-QTL (MQTL) for ear rot (ER) resistance Fig. 1 Projection on a reference map of chromosome 2.08 and 3.04 of MQTL for ear rot resistance in maize. The name of MQTL are on the left; names of markers and the distances in centimorgans are on the right. Acknowledgement The authors gratefully acknowledge Dr Yu-Ming Wei from Sichuan Agricultural University for excellent advice on QTL meta-analyses. In this study, bins 3.04 and 2.08 were major QTL containing regions of ER resistance (Fig. 1). Three MQTL (MQTL 8, 9 and 10) were located on bin 3.04, while another three MQTL (4, 5 and 6) were derived from bin Further fine mapping should be worthwhile in the two regions. a AER = Aspergillus ear rot, FER = Fusarium ear rot, GER = Gibberella ear rot
A quantitative trait locus not associated with cognitive ability in children: a failure to replicate Hill, L. et al.
1 15 The Genetic Basis of Complex Inheritance. 2 Multifactorial Traits Multifactorial traits are determined by multiple genetic and environmental factors.
1 14 Molecular Evolution and Population Genetics.
Miranda Durkie January Association is a statistical measure of the co- occurrence of certain phenotypic traits with certain alleles. An association.
Overweight/Obesity Transition over time among Sub-Saharan Africas School-Aged Children: Results from a Systematic Review. PASHDA Conference (March 2014)
Generalized Regional Admixture Mapping (RAM) and Structured Association Testing (SAT) David T. Redden, Associate Professor, Department of Biostatistics,
Analysis of Variance Chapter 12 McGraw-Hill/Irwin Copyright © 2012 by The McGraw-Hill Companies, Inc. All rights reserved.
SUMMARY Preliminary linkage maps of a Louisiana sugarcane cultivar, LCP , and its female (CP ) and male (CP ) parents were developed.
The Increased Burden of Community-Onset Clostridium difficile Infection Aaron Smith, B.S. 1, Brandon Wuerth, B.S. 1, Forest Arnold, D.O., M.Sc. 1 Department.
Conifer Translational Genomics Network Coordinated Agricultural Project Genomics in Tree Breeding and Forest Ecosystem Management.
Linkage and Genetic Mapping Lecture 1 Human Molecular Genetics (Strachan and Read) Chapters 4, 13, 14.
Zhiwu Zhang. Complex traits Controlled by multiple genes Influenced by environment Also known as quantitative traits Most traits are continuous, e.g.
C82MCP Diploma Statistics School of Psychology University of Nottingham 1 Overview of Lecture Parametric vs Non-Parametric Statistical Tests. Single Sample.
Pension statistics for the new ESA: compilation issues and some results for Portugal Workshop on the implementation of the 2008 SNA WPFS+WPNA | OECD,
1 Working Together to Assess Community Capacity Kathie Cram Community Development Consultant Public Health Services Saskatoon Health Region Saskatchewan,
1 Genes and Environment: Is it Nature or Nurture? Kenneth F. Schaffner, M.D., Ph.D. University Professor of Medical Humanities Professor of Philosophy.
Supplement 5 Comparison of homoeologous Kanota x Ogle (KO) linkage groups 24_26_34 and 22_44_18 and the location of As-Vrn1 mapped as an RFLP in KO. Stacked.
Maize Genetics, Genomics, Bioinformatics workshop Doreen Ware ARS USDA Cold Spring Harbor Laboratory.
Online Rubric Assessment Tool for Marine Engineering Course Dr. Cheng CHIN Newcastle University (in Singapore Campus) 1.
Briefing for Interagency Review June 4, 2012 Draft Proposal for the Particulate Matter (PM) National Ambient Air Quality Standards (NAAQS) Washington,
21-1 Copyright 2010 McGraw-Hill Australia Pty Ltd PowerPoint slides to accompany Croucher, Introductory Mathematics and Statistics, 5e Chapter 21 Hypothesis.
American Journal of Epidemiology Impact factor: Yr impact factor: Current Issue (Volume 175 Issue 5 March 1, 2012)
1 AU 350 SAS 111 Audit Sampling C Delano Gray June 14, 2008.
1 Joint Research Centre (JRC) * The views expressed in this paper belong to the authors and should not be attributed to the European Commission or its.
1 WATERSHED SPECIFIC AND REGIONAL SCALE SUSPENDED SEDIMENT LOAD ESTIMATES FOR BAY AREA SMALL TRIBUTARIES Mikołaj Lewicki and Lester McKee Sources Pathways.
Copyright © 2010, 2007, 2004 Pearson Education, Inc. All Rights Reserved. Lecture Slides Elementary Statistics Eleventh Edition and the Triola.
C82MST Statistical Methods 2 - Lecture 3 1 Overview of Lecture Partitioning Evaluating the Null Hypothesis ANOVA Basic Ratios Sums of Squares Mean Squares.
Molecular Genetic Methods in Psychology Tom Price.
Analysis of Variance Chapter 12 Copyright © 2011 by the McGraw-Hill Companies, Inc. All rights reserved. McGraw-Hill/Irwin.
© 2017 SlidePlayer.com Inc. All rights reserved.