1. Division of Tuberculosis Elimination Centers for Disease Control and Prevention Tuberculosis in the United States National Surveillance System Highlights from 2003

2. Reported TB Cases United States, 1982-2003 Year 1983 1987 1991 19951999 2003 No. of Cases 12,000 16,000 20,000 24,000 28,000

3. TB Morbidity United States, 1999-2003 Year Cases Rate* 199917,531 6.4 200016,377 5.8 200115,989 5.6 200215,075 5.2 200314,874 5.1 *Cases per 100,000

4. TB Case Rates,* United States, 2003 < 3.5 (year 2000 target) 3.6 - 5.1 > 5.1 (national average) D.C. *Cases per 100,000

5. TB Case Rates* by Age Group United States, 1993-2003 Age Group (years) Cases per 100,000 *Cases per 100,000.

6. Reported TB Cases by Age Group United States, 2003 25 - 44 yrs (34%) <15 yrs (6%) 15 - 24 yrs (11%) 45 - 64 yrs (29%) 65+ yrs (20%)

7. TB Case Rates* by Age Group and Sex, United States, 2003 Cases per 100,000 *Cases per 100,000.

8. TB Case Rates* by Race/Ethnicity** United States, 1993-2003 Cases per 100,000 WhiteBlack Hispanic American Indian/Alaska NativeAsian/Pacific Islander *Cases per 100,000. **All races are non-Hispanic. In 2003, Asian/Pacific Islander category includes persons who reported race as Asian only and/or Native Hawaiian or Other Pacific Islander only.

9. Reported TB Cases by Race/Ethnicity* United States, 2003 Hispanic or Latino (28%) Black or African American (28%) Asian (23%) White (19%) American Indian or Alaska Native (1%) Native Hawaiian or Other Pacific Islander (1%) *All races are non-Hispanic. Persons reporting two or more races comprised less than 1% of all cases.

10. TB Case Rates* by Age Group and Race/Ethnicity,** United States, 2003 Cases per 100,000 Age Group (yrs) *Cases per 100,000. **All races are non-Hispanic. Persons reporting two or more races comprised less than 1% of all cases. American Indian/Alaska Native Asian Black or African American Hispanic or Latino White Native Hawaiian/Other Pacific Islander

11. Number of TB Cases in U.S.-born vs. Foreign-born Persons United States, 1993-2003 No. of Cases

12. Trends in TB Cases in Foreign-born Persons, United States, 1986-2003 No. of CasesPercentage 00010203

13. Reported TB Cases by Origin and Race/Ethnicity,* United States, 2003 *All races are non-Hispanic. Persons reporting two or more races comprised less than 1% of all cases. **American Indian or Alaska Native and Native Hawaiian or Other Pacific Islander comprised less than 1% of foreign-born cases and are not shown. U.S.-bornForeign-born** Native Hawaiian/Other Pacific Islander (1%) White (34%) Black or African American (45%) Hispanic or Latino (15%) Asian (2%) American Indian or Alaska Native (3%) Hispanic or Latino (39%) Black or African American (13%) Asian (42%) White (5%)

14. Percentage of TB Cases Among Foreign-born Persons, United States >50% 25% - 49% <25% 19932003 DC

15. TB Case Rates* in U.S.-born vs. Foreign-born Persons United States, 1993-2003 Cases per 100,000 *Cases per 100,000

16. TB Case Rates* in U.S.-born vs. Foreign-born Persons United States, 1993-2003** Cases per 100,000 *Cases per 100,000 **Includes the same data as slide 15, but rates presented on a logarithmic scale.

17. Countries of Birth for Foreign-born Persons Reported with TB United States, 2003 Mexico (26%) Philippines (12%) Viet Nam (8%) India (8%) China (5%) Haiti (3%) S. Korea (2%) Other Countries (36%)

18. Length of U.S. Residence Prior to TB Diagnosis, United States, 2003

19. Primary Anti-TB Drug Resistance United States, 1993-2003 % Resistant Note: Based on initial isolates from persons with no prior history of TB. MDR TB defined as resistance to at least isoniazid and rifampin.

20. Primary MDR TB United States, 1993-2003 Note: Based on initial isolates from persons with no prior history of TB. MDR TB defined as resistance to at least isoniazid and rifampin. No. of Cases Percentage 00010203

21. Primary Isoniazid Resistance in U.S.-born vs. Foreign-born Persons United States, 1993-2003 Percentage Note: Based on initial isolates from persons with no prior history of TB.

22. Primary MDR TB in U.S.-born vs. Foreign-born Persons, United States, 1993-2003 % Resistant Note: Based on initial isolates from persons with no prior history of TB. MDR TB defined as resistance to at least isoniazid and rifampin.

23. % with Test Results Note: Includes cases with positive, negative, or indeterminate HIV test results and cases from California in persons reported with AIDS (HIV test results are not reported from California). Completeness of HIV Test Results in Persons with TB by Age Group United States, 1993-2002

24. Estimated HIV Coinfection in Persons Reported with TB, United States, 1993-2002 % Coinfection Note: Minimum estimates based on reported HIV-positive status among all TB cases in the age group.

25. Mode of Treatment Administration in Persons Reported with TB United States, 1993-2001 Directly observed therapy (DOT); Self-administered therapy (SA)

26. Completion of TB Therapy United States, 1993-2001 *Healthy People 2010 target: 90% completed in 1 yr or less. Note: Persons with initial isolate resistant to rifampin and children under 15 years old with meningeal, bone or joint, or miliary disease excluded. Percentage *