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Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian.

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Presentation on theme: "Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian."— Presentation transcript:

1 Progress Against Ovarian Cancer

2 1970–1979

3 Progress Against Ovarian Cancer 1970– : First effective combination chemotherapy regimen for ovarian cancer 1978: Cisplatin approved for advanced ovarian cancer

4 Progress Against Ovarian Cancer 1980–1989

5 Progress Against Ovarian Cancer 1980– : Oral contraceptives found to cut ovarian cancer risk

6 Progress Against Ovarian Cancer 1980–1989 Mid-1980s: Scientists discover ''biomarker'' tied to ovarian cancer – CA-125

7 Progress Against Ovarian Cancer 1980– : FDA approves carboplatin for ovarian cancer

8 Progress Against Ovarian Cancer 1990–1999

9 Progress Against Ovarian Cancer 1990– –1994: Taxanes emerge as vital chemotherapy option for ovarian, breast cancer

10 Progress Against Ovarian Cancer 1990– : New chemotherapy drug for advanced ovarian cancer

11 Progress Against Ovarian Cancer 1990–1999 Late 1990s: BRCA1 and BRCA2 gene mutations linked to increased ovarian cancer risk

12 Progress Against Ovarian Cancer 1990– : FDA approves liposomal doxorubicin for advanced ovarian cancer

13 Progress Against Ovarian Cancer 2000–Present

14 Progress Against Ovarian Cancer 2000–Present 2003: New chemotherapy regimen – docetaxel and paclitaxel – provides important treatment option

15 Progress Against Ovarian Cancer 2000–Present 2005: Researchers work to decode the ovarian cancer genome

16 Progress Against Ovarian Cancer 2000–Present 2006: Researchers find some ovarian cancers begin in the fallopian tubes 2006: Direct chemotherapy approach increases survival

17 Progress Against Ovarian Cancer 2000–Present Late 2000s: Researchers identify at least two ovarian cancer subtypes

18 Progress Against Ovarian Cancer 2000–Present 2009: Preventive surgery confirmed to reduce breast and ovarian cancer risk in women with BRCA gene mutations

19 Progress Against Ovarian Cancer 2000–Present 2010: Regular CA125 testing to monitor for ovarian cancer recurrence is questioned 2010: Bevacizumab significantly delays progression of advanced ovarian cancer 2010: Pre-surgery chemotherapy proven an effective option for women with advanced ovarian cancer

20 Progress Against Ovarian Cancer Five-Year Survival Source: National Cancer Institute

21 Progress Against Ovarian Cancer Mortality Source: National Cancer Institute

22 Progress Against Ovarian Cancer New Cases Source: National Cancer Institute

23 Visit CancerProgress.Net for an interactive timeline of progress against a range of common cancers CancerProgress.Net is a project of the American Society of Clinical Oncology, which represents nearly 30,000 physicians who treat people with cancer and research new cures


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