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The Nanomedicine Delivery Challenge. You have learned that some sunscreen products contain nanoscale structures. You have learned that some sunscreen.

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Presentation on theme: "The Nanomedicine Delivery Challenge. You have learned that some sunscreen products contain nanoscale structures. You have learned that some sunscreen."— Presentation transcript:

1 The Nanomedicine Delivery Challenge

2 You have learned that some sunscreen products contain nanoscale structures. You have learned that some sunscreen products contain nanoscale structures.

3 Nanoscale structures in sunscreen include clusters of zinc oxide and/or titanium oxide Different number of ions can cluster together. ZnO always has equal numbers of Zn and O ionsZnO always has equal numbers of Zn and O ions TiO 2 always has twice as many O ions as Ti ionsTiO 2 always has twice as many O ions as Ti ions ~100 nm TiO2 particle ~200 nm TiO 2 particle Source: Images adapted from

4 The unbalanced chemical equation below describes the formation of iron oxide structures commonly called magnetite. FeCl 3 + FeCl 2 + NH OH Fe 3 O 4 + NH 4 Cl FeCl 3 + FeCl 2 + NH OH Fe 3 O 4 + NH 4 Cl Water is used to rinse off the ammonium chloride.

5 A surfactant is then mixed with the iron oxide so that nanoscale clusters of iron oxide form.

6 The magnetite clusters can be put into a demonstration cell that contains an organic liquid. The clusters can be manipulated in a magnetic field and behave like a fluid. The magnetite clusters can be put into a demonstration cell that contains an organic liquid. The clusters can be manipulated in a magnetic field and behave like a fluid.

7 Ferrofluids as a model of a nanoscale medicine The goal for your group is to use the materials in the plastic containers to propose methods for delivering a nanoscale medicine to a specific location in the human body. The activity has been adapted from the November 2006 Science Scope Journal articleNanomedicine: Problem Solving to Treat Cancer co-authored by Melissa A. Hemling, Lauren M Samuel, Greta Zenner, Amy C. Payne, and Wendy C. Crone.

8 There are Three Data Tables In Data Table #1 you need to describe the effectiveness of medicine delivery devices. In Data Table #2 you need to compare the behaviors of nanoscale and larger than nanoscale particles in a magnetic field. In Data Table #3 you need to describe the possible advantages and disadvantages of a medicine that responds to a magnetic field.

9 Credits Slide 1: A manipulated nanoscale structure: Nanomedicine: Problem solving to treat cancer by Melissa A. Hemling, Lauren M. Samuel, Greta Zenner, Amy C. Payne, and Wendy C. Cron Science Scope Journal; November 2006 Slide 5 : FerroFluid Structure; Page 944 Journal of Chemical Education Vol. 76 No. 7 July 1999 JChemEd.chem.wisc.edu Slide 6: A FerroFluid display cell available from Educational Innovations Inc. At: YouTube video at:


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